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Metabolism of ¹⁴C Glycine - Glucose Melanoidin and Soybean Sauce
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¹⁴C Glycine - Glucose Melanoidin과 양조간장의 대사

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Type
Academic journal
Author
Journal
The korean Society of Food Science and Nutrition Journal of the Korean Society of Food Science and Nutrition Vol.23 No.2 KCI Accredited Journals SCOPUS
Published
1994.5
Pages
333 - 339 (7page)

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cover
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Topic
14C glycine-glucose melanoidin과 양조간장의 대사 과정을 규명하고 이들 물질의 대사적 특성을 비교하는 것이 본 연구의 주제이다.
📖
Background
Melanoidin은 강력한 항산화 효과를 가진 물질로 알려져 있으며, 양조간장이 중요한 조미료로 사용되고 있다는 점에서 이들의 대사 과정이 영양 생리에 미치는 영향이 크다.
🔬
Method
Wistar strain 수컷 쥐를 대상으로 14C glycine-glucose melanoidin과 양조간장을 경구로 투여하여 메타볼리즘을 연구하였다.
🏆
Result
투여 후 4일간의 실험에서 14C 활동량의 약 53%가 대변으로, 15%가 소변으로 배설되었으며, 나머지 47%는 체내에 보유되거나 대사된 것으로 보인다.
Metabolism of ¹⁴C Glycine - Glucose Melanoidin and Soybean Sauce
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Abstract· Keywords

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The metabolic transit of three samples (¹⁴C glycine-glucose melanoidin, glycine-glucose melanoidin and soybean sauce) were studied on rats. The radioactivity of various organs and excreta intubated ¹⁴C glycine-glucose melanoidin on rats at various intervals(l, 3, 8, 12, 24, 48, 72 and 96 hrs) were detected. And the brown pigment contents and hydrogen donating activities in the excreta which is obtained from three samples were detected during the 7 days after intubated. The total amounts of ¹⁴C excreted in the fecese were 53% meaning that the rest of 47% melanoidin seemed to be retained in the body or metabolized. The radioactive compound showed a small retention in the liver and kidney. The brown pigment contents and hydrogen donating activities in the urine and feces increased proportionally to the activity of ¹⁴C. When the soybean sauce and glycine glucose melanoidin were intubated, the brown pigment contents excreted in the feces were found to be the highest after 1st day of intubation. In the urine, the model melanoidin was excreted mostly after 3 days of intubation. The brown pigment contents and hydrogen donating activities of three samples of excreta agreed with each other. The soybean sauce retained longer than model melanoidin in the body is telling that it might have anti oxidative activity in vivo.

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Topic

14C glycine-glucose melanoidin과 양조간장의 대사 과정을 규명하고 이들 물질의 대사적 특성을 비교하는 것이 본 연구의 주제이다.

Background

Melanoidin은 강력한 항산화 효과를 가진 물질로 알려져 있으며, 양조간장이 중요한 조미료로 사용되고 있다는 점에서 이들의 대사 과정이 영양 생리에 미치는 영향이 크다.

Method

Wistar strain 수컷 쥐를 대상으로 14C glycine-glucose melanoidin과 양조간장을 경구로 투여하여 메타볼리즘을 연구하였다.

Result

투여 후 4일간의 실험에서 14C 활동량의 약 53%가 대변으로, 15%가 소변으로 배설되었으며, 나머지 47%는 체내에 보유되거나 대사된 것으로 보인다.

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