지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.9
- 수록면
- 267 - 273 (7page)
이용수
초록· 키워드
오류제보하기
Tungtungmadic acid (3-caffeoyl, 4-dihydrocaffeoyl quinic acid: CDCQ) is a new chlorogenic acid derivative isolated from the Salicornia herbacea. The suppressive effects of CDCQ on the progress of acute carbon tetrachloride (CC1₄)-induced hepatic fibrosis were investigated in mice. CDCQ significantly suppressed CCl₄-induced hepatic necrosis and inflammation, as determined by serum enzymatic activities of alanine and aspartate aminotransferase and serum TNF-α levels in a dose-dependent manner. In addition, increased hepatic lipid peroxidation and fibrosis after acute CCl₄ treatment were suppressed by the administration of CDCQ. CDCQ also significantly prevented the elevation of hepatic hydroxyproline and collagen content and α-smooth muscle actin (α-SMA) expression in the liver of CC1₄-intoxicated mice. These results suggest that the suppressive effects of CDCQ against the acute CC1₄-induced hepatic fibrosis possibly related to its ability to block both hepatic inflammation and the activation of hepatic stellate cells.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGMENTS
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Suppressive Effects of Platycodon grandiflorum on the Progress of Carbon Tetrachloride-Induced Hepatic Fibrosis
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
Inhibition of cyclooxygenase-2 expression by Caffeoyl-4-dihydrocaffeoyl quinic acid in macrophages
대한약학회 학술대회
2003 .01
-
Protective effects of Lipoic acid complex on CCl4-induced hepatic fibrosis in Sprague-Dawley rats
한국실험동물학회 학술발표대회 논문집
2005 .06
-
Hepatitis Virus Induced Hepatic Inflammation and Fibrosis
한국간담췌외과학회 학술대회지
2014 .04
-
Evaluation of disease severity using multimodal MR imaging in hepatic fibrosis animal model
한국실험동물학회 학술발표대회 논문집
2019 .07
-
Carbon tetrachloride (CCl4)-induced liver fibrosis through activation of hepatic stellate cells by activation of RelA/p65 and alpha‐smooth muscle actin in mice
한국실험동물학회 학술발표대회 논문집
2015 .08
-
An aqueous extract isolated from Platycodon grandiflorum reduced acetaldehyde-induced collagen and alpha-SMA expression in hepatic stellate cells
대한약학회 학술대회
2003 .01
-
Role of Hepatic Innate Immunity in Hepatic Fibrosis : Toll-like Receptor and NK Cell
한국간담췌외과학회 학술대회지
2014 .04
-
Tungtungmadic Acid, a Novel Antioxidant, from Salicornia her-bacea
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2005 .01
-
Effects of HepacureⓇ on Dmn Induced Hepatic Fibrosis in Rat
한국실험동물학회 학술발표대회 논문집
2004 .06
-
Sinusoidal Endothelial Cell and Hepatic Fibrosis
한국간담췌외과학회 학술대회지
2014 .04
-
Ginseng essence, a medicinal and edible herbal formulation, ameliorates carbon tetrachloride-induced oxidative stress and liver injury in rats
Journal of Ginseng Research
2017 .07
-
Antifibrotic activity a fermentation filtrate of Ganoderma lucidum
Laboratory Animal Research
2011 .12
-
Autophagy regulatory molecules in hepatic stellate cells for liver fibrosis
한국실험동물학회 학술발표대회 논문집
2018 .07
-
Non-alcoholic Fatty Liver Disease (NAFLD) and Significant Hepatic Fibrosis Defined by Non-invasive Assessment in Patients with Type 2 Diabetes
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Inhibition of hepatic stellate cell collagen synthesis by an aqueous extract isolated from Platycodon grandiflorum
대한약학회 학술대회
2003 .01
-
Role of RelA/p65 and α-smooth muscle actin of activated hepatic stellate cell in carbon-tetrachloride-induced liver cirrhosis
한국실험동물학회 학술발표대회 논문집
2015 .02
-
CC14-induced Lipid Peroxidation and Acute Liver Fibrosis in the Rat
대한약학회 학술대회
2002 .01
-
Regulation of Pathological Markers during Hepatic Fibrogenesis in Rats
한국수의병리학회 학술발표논문집
2003 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-513-017426710