지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.12 No.1
- 발행연도
- 2007.3
- 수록면
- 1 - 6 (6page)
이용수
초록· 키워드
오류제보하기
Colostrum basic proteins (CBP) (MW 1～30 kDa) were isolated from bovine colostrum using a series of ultrafiltration processes and their effects on osteoblast cell proliferation and bone metabolism were investigated in cell line and animal models. Treatments with CBP (1, 10, 100 ㎍/mL) dose-dependently increased cell proliferation of osteoblastic MC3T3 cells. Alkaline phosphatase activity, a marker of osteoblastic phenotype, in the cells was also increased after treatments with CBP in a dose-dependent manner. Significant increases in bone density were observed in femur of ovariectomized rats which were fed a diet with 1% and 10% CBP, compared to rats fed a normal diet. These results suggest that CBP may increase bone mass and density and be useful for the prevention of bone-related diseases.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (37)
참고문헌 신청
Briese V, Straube W. 1986. Immunology of the fetomaternal interation: immunologic significance of colostrum and breas milk. Zentralbl Gynaekol 108: 73-83.
Davis DP. 1989. How suitable is human milk for pre-term babies? Acta Paediatr Jpn 31: 439-454.
Jayashree SM, Bhan MK, Kumar R, Bhandari N, Sazawal S. 1988. Protection against neonatal rotavirus infection by breast milk antibodies and trypsin inhibitors. J Med Virol 26: 333-338.
Aynsley-Green A. 1989. New insights into the nutritional management of newborn infants derived from studies of metabolic and endocrine inter-relations during the adaptation to post-natal life. Proc Nutr Soc 48: 283-292.
Carmichael RD, LoBue J, Gordon AS. 1992. Neonatal erythropoiesis. II. Bone marrow and splenic erythropoietic activity: data suggest erythropoietin transfer via maternal milk. Endocr Regul 26: 143-149.
Davis DP. 1989. How suitable is human milk for pre-term babies? Acta Paediatr Jpn 31: 439-454.
Jayashree SM, Bhan MK, Kumar R, Bhandari N, Sazawal S. 1988. Protection against neonatal rotavirus infection by breast milk antibodies and trypsin inhibitors. J Med Virol 26: 333-338.
Aynsley-Green A. 1989. New insights into the nutritional management of newborn infants derived from studies of metabolic and endocrine inter-relations during the adaptation to post-natal life. Proc Nutr Soc 48: 283-292.
Carmichael RD, LoBue J, Gordon AS. 1992. Neonatal erythropoiesis. II. Bone marrow and splenic erythropoietic activity: data suggest erythropoietin transfer via maternal milk. Endocr Regul 26: 143-149.
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