지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.9
- 수록면
- 209 - 213 (5page)
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The frequencies of gamma-ray-induced micronuclei (MN) in cytokinesis-blocked (CB) lymphocytes at several low doses (0, 246, 492, 739, 985 and 1,969 mGy) were measured in three donors of cattle and pig. Measurements performed after irradiation showed a dose-related increases in MN frequency in each of the donors studied. When analysed by linear-quadratic model the line of best fit was: cattle: y = 0.0583D + 0.0366D² + 0.0093, pig : y = 0.0424D + 0.00054D² + 0.0083 (y = number of MN/CB cells and D = irradiation dose in Gy). The relative sensitivity of pig lymphocytes compared with cattle lymphocytes was estimated by best fitting linear-quadratic model based on the radiation-induced MN data over the range from 0 Gy to 1,969 mGy. In the case of MN frequency with 0.0125, 0.025, 0.05, 0.1 and 0.2, the relative sensitivities of pig lymphocytes were 0.84, 0.60, 0.54, 0.46 and 0.38 respectively. These data indicate that the induction of MN in CB cells from pigs were much less sensitive to the MN induction effects of low dose gamma-radiation than those from cattles. Our in vitro radiobiological study confirmed that the cytogenetic response obtained in blood from cattle and pig can be utilized for application in environmental studies.
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UCI(KEPA) : I410-ECN-0101-2009-510-016363037