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자료유형
학술저널
저자정보
Shin-Moo Kim (원광보건대학) Dong-Cho Lee (원광대학교병원) Seok-Don Park (원광대학교병원) Bo-Suk Kim (원광대학교병원) Jin-Kyung Kim (원광대학교) Mi-Rae Choi (원광보건대학) Se-Young Park (원광대학교병원) Soo-Myung Hwang (부산가톨릭대학교) Na-Young Shin (가톨릭대학교) Eun-Sook Shim (원광보건대학) Pil-Seung Kwon (원광보건대학) Dong-Yeul Kwon (원광대학교) Sung-Ho Hur (동의대학교) Ho-Jun Kim (순천대학교) Hyo-Bin Lim (원광대학교) Yunsop Chong (연세대학교)
저널정보
대한미생물학회 JOURNAL OF BACTERIOLOGY AND VIROLOGY JOURNAL OF BACTERIOLOGY AND VIROLOGY Vol.39 No.4
발행연도
2009.12
수록면
307 - 316 (10page)

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Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent dermatology pathogens in hospitals and increasingly recognized in communities. We determined PFGE pattern of SmaI-restricted genomic DNA, coagulase type, and antimicrobial susceptibility of MRSA isolated in 2008 from dermatology inpatients and healthy hospital employees in A Hospital and from primary school children in Iksan city, Korea. Overall, the isolation rate of MRSA was 3.8% from the 788 normal persons: 4.9% from hospital employees and 1.1% from primary school children. MRSA was isolated in six of 13 (46.2%) family members of four school children with MRSA. The most prevalent coagulase serotype was Ⅱ from patients and V from healthy individuals. Ten of twenty and six of twenty MRSA isolates from patients and from healthy personnel, respectively, had identical PFGE patterns, suggesting that these are originated from identical clones. Against MRSA from patients, only vancomycin was the most active (MIC range ≤2 μg/㎖), whereas the resistance rates were 35% to rifampin and 65% to mupirocin. The resistance rates of patient isolates were ≥90% to amikacin, clindamycin, ciprofloxacin, erythromycin, fusidic acid, gentamicin and tetracycline. In conclusion, the MRSA carriage rates of healthy hospital workers were relatively high, 2.3~7.7%, depending on groups. Family members of a few primary school children with MRSA showed a high carriage rate, suggesting that intrafamily transmission occurred. MRSAs isolated from dermatology inpatients were relatively more resistant to various antimicrobial agents, including mupirocin, but all isolates were susceptibility to vancomycin.

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