지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.6
- 수록면
- 235 - 242 (8page)
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초록· 키워드
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To obtain microorganisms for the microbial conversion of ginsenosides in red ginseng extract (RGE), mushroom mycelia were used for the fermentation of RGE. After fermentation, total sugar contents and polyohenol contents of the RGEs fermented with various mushrooms were not a significant increase between RGE and the ferments. But uronic acid content was relatively higher in the fermented RGEs cultured with Lentus edodes (2155.6 ㎍/mL), Phelllinus linteus (1690.9 ㎍/mL) and Inonotus obliquus 26137 and 26147 (1549.5 and 1670.7 ㎍/mL) compared to the RGE (1307.1 ㎍/mL). The RGEs fermented by Ph. linteus, Cordyceps militaris, and Grifola frondosa showed particularly high levels of total ginsenosides (20018.1, 17501.6, and 16267.0 ㎍/mL, respectively). The ferments with C. militaris (6974.2 ㎍/mL), Ph. linteus (9109.2 ㎍/mL), and G. frondosa (7023.0 ㎍/mL) also showed high levels of metabolites (sum of compound K, Rh₁, Rg?, Rk₁, Rg₃, and Rg₂) compared to RGE (3615.9 ㎍/mL). Among four different RGE concentrations examined, a 20 brix concentration of RGE was favorable for the fermentation of Ph. linteus. Maximum biotransformation of ginsneoside metabolites (9395.5 ㎍/mL) was obtained after 5 days fermentation with Ph. linteus. Maximum mycelial growth of 2.6 ㎎/mL was achieved at 9 days, in which growth was not significantly different during 5 to 9 days fermentation. During fermentation of RGE by Ph. linteus in a 7 L fermenter, Rg₃, Rg?, and Rk₁ contents showed maximum concentrations after 5 days similar to flask fermentation. These results confirm that fermentation with Ph. linteus is very useful for preparing minor ginsenoside metabolites while being safe for foods.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (35)
참고문헌 신청
1. [학술지(정기간행물)] - Lu JM / 2009 / Ginseng compounds: an update on their molecular mechanisms and medical applications / Curr Vasc Pharmacol 7 : 293 ~ 302
2. [학술지(정기간행물)] - Dey L / 2002 / Anti-diabetic and anti-obese effects of ginseng berry extract: comparison between intraperitoneal and oral administrations / Am J Chin Med 30 : 645 ~ 647
3. [학술지(정기간행물)] - He W / 2008 / Inhibitory effects of ginsenosides from the root of Panax ginseng on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation, and translocation of cytosolic compounds to plasma membrane in human neutrophils / J Agric Food Chem 56 : 1921 ~ 1927
4. [학술지(정기간행물)] - Lee SJ / 1999 / Antitumor activity of a novel ginseng saponin metabolite in human pulmonary adenocarcinoma cells resistant to cisplatin / Cancer Lett 144 : 39 ~ 43
5. [학술지(정기간행물)] - Hyun-Jeong Kim / 2010 / Effects of Fermented Red Ginseng Extracts on Hyperglycemia in Streptozotocin-induced Diabetic Rats / Journal of Ginseng Research 34 (2) : 104 ~ 112
2. [학술지(정기간행물)] - Dey L / 2002 / Anti-diabetic and anti-obese effects of ginseng berry extract: comparison between intraperitoneal and oral administrations / Am J Chin Med 30 : 645 ~ 647
3. [학술지(정기간행물)] - He W / 2008 / Inhibitory effects of ginsenosides from the root of Panax ginseng on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation, and translocation of cytosolic compounds to plasma membrane in human neutrophils / J Agric Food Chem 56 : 1921 ~ 1927
4. [학술지(정기간행물)] - Lee SJ / 1999 / Antitumor activity of a novel ginseng saponin metabolite in human pulmonary adenocarcinoma cells resistant to cisplatin / Cancer Lett 144 : 39 ~ 43
5. [학술지(정기간행물)] - Hyun-Jeong Kim / 2010 / Effects of Fermented Red Ginseng Extracts on Hyperglycemia in Streptozotocin-induced Diabetic Rats / Journal of Ginseng Research 34 (2) : 104 ~ 112
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