지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.9
- 수록면
- 453 - 458 (6page)
이용수
초록· 키워드
오류제보하기
The MC1R (Melanocortin 1 receptor) gene has been known as a causative gene of the coat colors in mammals and responsible for the E (Extension) locus which has three alleles (E<SUP>D</SUP>, E<SUP>+</SUP>, e) that determines coat colors. The dominant allele E<SUP>D</SUP> produces black or brown colors due to the missense mutation and the recessive e allele has frameshift mutation which shows red or yellow coat colors. Whereas the wild type E<SUP>+</SUP> produces variety of colors due to the interaction with A (Agouti) locus. In this study, PCR-RFLP was performed using two restriction enzymes (BsrF I and MspA1 I) in order to obtain MC1R genotypes in Korean brindle cattle and black cattle. The results showed that all of the animals have the E<SUP>+</SUP> alleles, indicating the E<SUP>+</SUP> allele might related with black coat colors. Later on, the experiments expanded to the 260 Korean candidate bulls whether these animals have the same E<SUP>+</SUP> allele. Among 260 samples investigated, 5% (13/260) of the animals had E+e genotypes, indicating the E<SUP>+</SUP> allele is also present in the candidate bulls in a low frequency. Even though we expected that A locus also affect the black coat color in cattle, all the black coat color animals (brindle and black) have E<SUP>+</SUP> alleles in this study. Therefore, the genotyping of the MC1R gene in candidate bulls will recommended be applied for eliminating of black coat colors in Hanwoo population, if the farmers need to have the brown coat colors only.
목차
Abstract
Ⅰ. 서론
Ⅱ. 재료 및 방법
Ⅲ. 결과 및 고찰
Ⅳ. 결론
참고문헌
참고문헌 (12)
참고문헌 신청
1. [학술지(정기간행물)] - Adalsteinsson S / 1995 / Brown coat color in Icelandic cattle produced by the loci Extension and Agouti / J. Hered 86 (5) : 395 ~ 398
2. [학술지(정기간행물)] - Charlier C / 1996 / Microsatellite mapping of the bovine roan locus - a major determinant of white heifer disease / Mamm. Genome 7 : 138 ~ 142
3. [학술지(정기간행물)] - Guibert S / 2004 / Pheomelanin coat colour dilution in French cattle breeds is not correlated with the TYR, TYRP1 and DCT transcription levels / Pigment Cell Res 17 : 337 ~ 345
4. [학술지(정기간행물)] - 한상현 / 2011 / Coat Color Patterns and Genotypes of Extension and Agouti in Hanwoo and Jeju Black Cattle / 생명과학회지 21 (4) : 494 ~ 501
5. [학술지(정기간행물)] - Hearing VJ / 1991 / Enzymatic control of pigmentation in mammals / FASEB J 5 (14) : 2902 ~ 2909
2. [학술지(정기간행물)] - Charlier C / 1996 / Microsatellite mapping of the bovine roan locus - a major determinant of white heifer disease / Mamm. Genome 7 : 138 ~ 142
3. [학술지(정기간행물)] - Guibert S / 2004 / Pheomelanin coat colour dilution in French cattle breeds is not correlated with the TYR, TYRP1 and DCT transcription levels / Pigment Cell Res 17 : 337 ~ 345
4. [학술지(정기간행물)] - 한상현 / 2011 / Coat Color Patterns and Genotypes of Extension and Agouti in Hanwoo and Jeju Black Cattle / 생명과학회지 21 (4) : 494 ~ 501
5. [학술지(정기간행물)] - Hearing VJ / 1991 / Enzymatic control of pigmentation in mammals / FASEB J 5 (14) : 2902 ~ 2909
이 논문의 저자 정보
이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2013-480-000772964