지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 93 - 101 (9page)
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초록· 키워드
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This study evaluated the anti-cholinesterases (ChEs) and antioxidant activities of white ginseng (WG) and black ginseng (BG) roots of Panax ginseng (PG), P. quinquefolium (PQ), and P. notoginseng (PN). Ginsenosides Rg₁, Re, Rf, Rb₁, Rc, Rb₂, and Rd were found in white PG, whereas Rf was not found in white PQ and Rf, Rc, and Rb2 were not detected in white PN. The major ginsenoside content in steamed BG including RK₃, Rh₄, and 20(S)/(R)-Rg₃ was equivalent to approximately 70% of the total ginsenoside content. The WG and BG inhibited acetylcholinesteras (AChE) and butyrylcholinesterase (BChE) in a dose dependent manner. The efficacy of BG roots of PG, PQ, and PN on AChE and BChE inhibition was greater than that of the respective WG roots. The total phenolic contents and 2, 2-diphenyl-1-picryl-hydrazyl (DPPH) scavenging activity were increased by heat treatment. Among the three WG and BG, white PG and steamed black PQ have signifi cantly higher contents of phenolic compounds. The best results for the DPPH scavenging activity were obtained with the WG and BG from PG. These results demonstrate that the steamed BG roots of the three studied ginseng species have both high ChEs inhibition capacity and antioxidant activity.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (35)
참고문헌 신청
Tang W. / 1992 / Panax ginseng C. A. Meyer, In Chinese drugs of plant origin: chemistry, pharmacology, and use in traditional and modern medicine / Springer :711~737
Sun BS. / 2009 / Simultaneous quantifi cation of 19 ginsenosides in black ginseng developed from Panax ginseng by HPLC-ELSD / J Pharm Biomed Anal 50:15~22
Lu GH. / 2008 / Differentiation of Asian ginseng, American ginseng and notoginseng by Fourier transform infrared spectroscopy combined with two-dimensional correlation infrared spectroscopy / J Mol Struct 883-884:91~98
Kang KS. / 2007 / Increase in the free radical scavenging activities of American ginseng by heat processing and its safety evaluation / J Ethnopharmacol 113:225~232
Ng TB. / 2006 / Pharmacological activity of sanchi ginseng(Panax notoginseng) / J Pharm Pharmacol 58:1007~1019
Sun BS. / 2009 / Simultaneous quantifi cation of 19 ginsenosides in black ginseng developed from Panax ginseng by HPLC-ELSD / J Pharm Biomed Anal 50:15~22
Lu GH. / 2008 / Differentiation of Asian ginseng, American ginseng and notoginseng by Fourier transform infrared spectroscopy combined with two-dimensional correlation infrared spectroscopy / J Mol Struct 883-884:91~98
Kang KS. / 2007 / Increase in the free radical scavenging activities of American ginseng by heat processing and its safety evaluation / J Ethnopharmacol 113:225~232
Ng TB. / 2006 / Pharmacological activity of sanchi ginseng(Panax notoginseng) / J Pharm Pharmacol 58:1007~1019
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UCI(KEPA) : I410-ECN-0101-2013-524-001261198