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학술대회자료
저자정보
김영태 (강원대학교) 정의철 (강원대학교) 안정민 (울산대학교 서울아산병원) 박승정 (울산대학교 서울아산병원) 심은보 (강원대학교)
저널정보
한국전산유체공학회 한국전산유체공학회 학술대회논문집 한국전산유체공학회 2012년도 춘계학술대회 논문집
발행연도
2012.5
수록면
144 - 147 (4page)

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Fractional flow reserve (FFR) which is a guidewire-based measure has been a major clinical index for diagnosis of coronary stenotic severity. However, it is clinically observed both of proximal and distal FFRs in a tandem double stenotic lesion are mutually interfered. Thus, recently an alternative clinical index, delta-delta FFR (dd-FFR) was introduced for relevant diagnosis of relative stenotic severity between the two stenoses. Nevertheless, if there is the effect of bifurcation between the two stenoses on the dd-FFR has been a new clinical issue to be proved even with the change of the diameter of the bifurcated branch. Therefore, in this work 3D virtual tandem double coronary bifurcation (TDCB) models which have three different diameters of a bifurcated branch were designed and fluid dynamics simulation was performed. For proper coronary pressure-flow rate relation a porous media model was incorporated to mimic clinical autonomous regulation of the myocardial microvascular resistance. Clinically reasonable flow distribution between the main and bifurcated branches was achieved by vascular area-based flow distribution and proper distal coronary pressure conditions. For a TDCB model, four virtual models: normal, two single stenotic (proximal and distal, respectively), and TDCB models were constructed to achieve more reasonable pressure-flow rate relation in the TDCB models. Computed results showed that the bifurcation between the double stenoses does not significantly affect on the diagnosis of relative severity of the double stenoses with the dd-FFR even with the variable diameter of the bifurcated branch.

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UCI(KEPA) : I410-ECN-0101-2013-422-002847906