지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 16 - 22 (7page)
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Purpose: The prognosis for gastric cancer patients with distant metastasis is very poor. The purpose of this study was to evaluate the prognosis and survival for gastric cancer patients with synchronous metastasis.
Methods: Among 2,083 gastric cancer patients who received surgery at the Department of Surgery, Hanyang University Hospital from 1992 to 2009, 164 patients revealed distant metastasis. However, 3 patients who died of postoperative complications were excluded. For the remaining patients, various clinicopathological factors were analyzed using univariate and multivariate survival analyses.
Results: Systemic chemotherapy (SC), type of surgery, lymph node dissection, degree of peritoneal carcinomatosis (PC), presence of ascites and tumor location were significant prognostic factors. However, sex, age, number of metastatic sites and histologic classification were not significant prognostic factors. In multivariate analysis, the type of surgery, the SC and the degree of PC were independent prognostic factors. Survival benefit by SC was significant in single site metastasis. The significant survival difference between resection and non-resection groups was observed regardless of number of metastatic sites.
Conclusion: In gastric cancer patients with metastasis, the favorable prognostic factors were type of surgery and SC in single metastasis. The gastrectomy improves the prognosis regardless of number of metastatic sites. However, a prospective randomized clinical trial is mandatory to attain more accurate information.
Methods: Among 2,083 gastric cancer patients who received surgery at the Department of Surgery, Hanyang University Hospital from 1992 to 2009, 164 patients revealed distant metastasis. However, 3 patients who died of postoperative complications were excluded. For the remaining patients, various clinicopathological factors were analyzed using univariate and multivariate survival analyses.
Results: Systemic chemotherapy (SC), type of surgery, lymph node dissection, degree of peritoneal carcinomatosis (PC), presence of ascites and tumor location were significant prognostic factors. However, sex, age, number of metastatic sites and histologic classification were not significant prognostic factors. In multivariate analysis, the type of surgery, the SC and the degree of PC were independent prognostic factors. Survival benefit by SC was significant in single site metastasis. The significant survival difference between resection and non-resection groups was observed regardless of number of metastatic sites.
Conclusion: In gastric cancer patients with metastasis, the favorable prognostic factors were type of surgery and SC in single metastasis. The gastrectomy improves the prognosis regardless of number of metastatic sites. However, a prospective randomized clinical trial is mandatory to attain more accurate information.
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REFERENCES
참고문헌 (30)
참고문헌 신청
1. [단행본] - Cheung LY / 2001 / Gastric cancer, In Sabiston Textbook of Surgery. 16th ed / W.B. Saunders : 855 ~ 865
2. [학술지(정기간행물)] - Jemal A / 2004 / Cancer statistics / CA Cancer J Clin 54 : 8 ~ 29
3. [단행본] - / 2000 / Annual Report on the Cause of Death Statistics (Based on Vital Registration) / National Statistical Office
4. [단행본] - Central Cancer Registry in Korea / 2000 / Annual Report of the Central Cancer Registry in Korea / Ministry of Health and Welfare
5. [학술지(정기간행물)] - Park JH / 1992 / Clinical analysis of gastric adenocarcinoma experienced during recent 10 years and follow up results / J Korean Surg Soc 42 : 787 ~
2. [학술지(정기간행물)] - Jemal A / 2004 / Cancer statistics / CA Cancer J Clin 54 : 8 ~ 29
3. [단행본] - / 2000 / Annual Report on the Cause of Death Statistics (Based on Vital Registration) / National Statistical Office
4. [단행본] - Central Cancer Registry in Korea / 2000 / Annual Report of the Central Cancer Registry in Korea / Ministry of Health and Welfare
5. [학술지(정기간행물)] - Park JH / 1992 / Clinical analysis of gastric adenocarcinoma experienced during recent 10 years and follow up results / J Korean Surg Soc 42 : 787 ~
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