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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.7
- 수록면
- 8 - 13 (6page)
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Purpose: Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic adjustable gastric banding (LAGB) are the most effective intervention and cure in achieving sustained weight loss in the morbidly obese with co-morbities, especially in type 2 diabetes mellitus (DM). Currently, there are few data in the literature presenting early diabetic outcomes between the 2 major bariatric surgeries in Korea. The aim of this study is to observe weight loss, improvement of type 2 DM after LRYGB and LAGB.
Methods: 33 retrospective data were obtained from diabetic subjects undergoing LRYGB (n=53) and LAGB (n=77). These measurements included age, sex, body mass index (BMI), pre-operative diabetic duration, post-operative diabetic at follow-up visit after surgery. Paired t-test, and SPSS12.0 were used for statistical analysis.
Results: 33 morbidly obese patients with type 2 DM who had both procedures complain of general weakness. Most patients were taking oral medications or insulin and tired of them. Pre and post-op 12 months of percent of excess weight loss (%EWL), fetal bovine serum (FBS), hemoglobin A1c (HbA1C) presented at 0%, 185.6 ㎎/㎗, 8.7% and 70.6%, 123.4 ㎎/㎗, 6.6% in patients who had LRYGB (P＜0.05). Pre and post-op 12 months of %EWL, FBS, HbA1C presented at 0%, 180.6 ㎎/㎗, 8.4% and 32.8%, 136.5 ㎎/㎗, 6.8% in patients who had LAGB (P＜0.05). Rate of discontinuance or decreasing for treatment of type 2 DM after surgery showed 94% for LRYGB versus 80% for LAGB, and unchanged rates were 6% versus 20%, respectively.
Conclusion: This study showed LRYGB and LAGB are quite satisfactory and promising bariatric procedures with significant weight loss and improvement of type 2 DM in Koreans. LRYGB is significantly associated with more weight loss, more diabetic outcome than LAGB. Clinical experiences in Korea with both procedures are limited and a larger number of cases are need, but the recent data shows promising results that are comparable to the international experience.
Methods: 33 retrospective data were obtained from diabetic subjects undergoing LRYGB (n=53) and LAGB (n=77). These measurements included age, sex, body mass index (BMI), pre-operative diabetic duration, post-operative diabetic at follow-up visit after surgery. Paired t-test, and SPSS12.0 were used for statistical analysis.
Results: 33 morbidly obese patients with type 2 DM who had both procedures complain of general weakness. Most patients were taking oral medications or insulin and tired of them. Pre and post-op 12 months of percent of excess weight loss (%EWL), fetal bovine serum (FBS), hemoglobin A1c (HbA1C) presented at 0%, 185.6 ㎎/㎗, 8.7% and 70.6%, 123.4 ㎎/㎗, 6.6% in patients who had LRYGB (P＜0.05). Pre and post-op 12 months of %EWL, FBS, HbA1C presented at 0%, 180.6 ㎎/㎗, 8.4% and 32.8%, 136.5 ㎎/㎗, 6.8% in patients who had LAGB (P＜0.05). Rate of discontinuance or decreasing for treatment of type 2 DM after surgery showed 94% for LRYGB versus 80% for LAGB, and unchanged rates were 6% versus 20%, respectively.
Conclusion: This study showed LRYGB and LAGB are quite satisfactory and promising bariatric procedures with significant weight loss and improvement of type 2 DM in Koreans. LRYGB is significantly associated with more weight loss, more diabetic outcome than LAGB. Clinical experiences in Korea with both procedures are limited and a larger number of cases are need, but the recent data shows promising results that are comparable to the international experience.
목차
서론
방법
결과
고찰
결론
REFERENCES
참고문헌 (12)
참고문헌 신청
1. [학술지(정기간행물)] - Cummings S / 2008 / Obesity surgery: evidence for diabetes prevention/management / J Am Diet Assoc 108 : S40 ~ 44
2. [학술지(정기간행물)] - Schauer PR / 2003 / Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus / Ann Surg 238 : 467 ~ 484
3. [학술지(정기간행물)] - Sugerman HJ / 2003 / Diabetes and hypertension in severe obesity and effects of gastric bypass- induced weight loss / Ann Surg 237 : 751 ~ 756
4. [학술지(정기간행물)] - Guidone C / 2006 / Mechanisms of recovery from type 2 diabetes after malabsorptive bariatric surgery / Diabetes 55 : 2025 ~ 2031
5. [학술지(정기간행물)] - Rosa G / 2007 / Molecular mechanisms of diabetes reversibility after bariatric surgery / Int J Obes (Lond) 31 : 1429 ~ 1436
2. [학술지(정기간행물)] - Schauer PR / 2003 / Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus / Ann Surg 238 : 467 ~ 484
3. [학술지(정기간행물)] - Sugerman HJ / 2003 / Diabetes and hypertension in severe obesity and effects of gastric bypass- induced weight loss / Ann Surg 237 : 751 ~ 756
4. [학술지(정기간행물)] - Guidone C / 2006 / Mechanisms of recovery from type 2 diabetes after malabsorptive bariatric surgery / Diabetes 55 : 2025 ~ 2031
5. [학술지(정기간행물)] - Rosa G / 2007 / Molecular mechanisms of diabetes reversibility after bariatric surgery / Int J Obes (Lond) 31 : 1429 ~ 1436
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