지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.7
- 수록면
- 43 - 49 (7page)
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초록· 키워드
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Purpose: Apocrine carcinoma is a rare type of breast carcinoma, which has not been fully investigated. The aim of this study was to review clinicopathological features of apocrine carcinoma of the breast and to determine if there are some characteristics different from invasive ductal carcinoma.
Methods: There were 4,064 breast cancer patients who had been managed in the Department of Surgery of Yonsei University College of Medicine from January 1997 to January 2008. Out of the patients, 16 patients with apocrine carcinoma and 2,997 patients with invasive ductal carcinoma were analyzed retrospectively.
Results: The incidence of apocrine carcinoma was 0.4%. Most of the clinicopathologic features of apocrine carcinoma were similar to those of invasive ductal carcinoma. The percentage of estrogen receptor (ER) positivity and progesterone receptor (PR) positivity of apocrine carcinoma were all 12.5%. And the percentage of ER positivity and PR positivity of invasive ductal carcinoma were 64.2% and 55.2% respectively. Androgen receptor was only examined for eleven patients out of the 16 patients with apocrine carcinoma and the result were all positive.
Conclusion: Apocrine carcinoma is also a rare disease in Korea. When compared with invasive ductal carcinoma, the disease did not appear to show any other significant difference in clinicopathologic characteristics but the percentages of ER and PR positivity of apocrine carcinoma seemed lower than those of invasive ductal carcinoma.
Methods: There were 4,064 breast cancer patients who had been managed in the Department of Surgery of Yonsei University College of Medicine from January 1997 to January 2008. Out of the patients, 16 patients with apocrine carcinoma and 2,997 patients with invasive ductal carcinoma were analyzed retrospectively.
Results: The incidence of apocrine carcinoma was 0.4%. Most of the clinicopathologic features of apocrine carcinoma were similar to those of invasive ductal carcinoma. The percentage of estrogen receptor (ER) positivity and progesterone receptor (PR) positivity of apocrine carcinoma were all 12.5%. And the percentage of ER positivity and PR positivity of invasive ductal carcinoma were 64.2% and 55.2% respectively. Androgen receptor was only examined for eleven patients out of the 16 patients with apocrine carcinoma and the result were all positive.
Conclusion: Apocrine carcinoma is also a rare disease in Korea. When compared with invasive ductal carcinoma, the disease did not appear to show any other significant difference in clinicopathologic characteristics but the percentages of ER and PR positivity of apocrine carcinoma seemed lower than those of invasive ductal carcinoma.
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REFERENCES
참고문헌 (23)
참고문헌 신청
1. [학술지(정기간행물)] - Peters GN / 1981 / Tubular carcinoma of the breast. Clinical pathologic correlations based on 100 cases / Ann Surg 193 : 138 ~ 149
2. [학술지(정기간행물)] - Ridolfi RL / 1977 / Medullary carcinoma of the breast: a clinicopathologic study with 10 year follow-up / Cancer 40 : 1365 ~ 1385
3. [학술지(정기간행물)] - Di Saverio S / 2008 / A retrospective review with long term follow up of 11,400 cases of pure mucinous breast carcinoma / Breast Cancer Res Treat 111 : 541 ~ 547
4. [학술지(정기간행물)] - Mossler JA / 1980 / Apocrine differentiation in human mammary carcinoma / Cancer 46 : 2463 ~ 2471
5. [단행본] - Bonser GM / 1961 / Human and Experimental Breast Cancer / Pitman
2. [학술지(정기간행물)] - Ridolfi RL / 1977 / Medullary carcinoma of the breast: a clinicopathologic study with 10 year follow-up / Cancer 40 : 1365 ~ 1385
3. [학술지(정기간행물)] - Di Saverio S / 2008 / A retrospective review with long term follow up of 11,400 cases of pure mucinous breast carcinoma / Breast Cancer Res Treat 111 : 541 ~ 547
4. [학술지(정기간행물)] - Mossler JA / 1980 / Apocrine differentiation in human mammary carcinoma / Cancer 46 : 2463 ~ 2471
5. [단행본] - Bonser GM / 1961 / Human and Experimental Breast Cancer / Pitman
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