지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.9
- 수록면
- 171 - 176 (6page)
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초록· 키워드
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Purpose: This study investigated the clinical features of patients with thyroid nodule combined with Hashimoto’s thyroiditis, and the latter was incidentally detected after surgery.
Methods: The authors retrospectively evaluated 43 patients who were diagnosed with Hashimoto’s thyroiditis after thyroidectomy between January 2001 and December 2006 at Chosun University Hospital.
Results: All patients underwent ultrasonography for the diagnosis of thyroid nodules. Ultrasonography revealed 16 calcified nodules with ill-defined margins, and these nodules were suspicious for malignancy. On performing preoperative fine needle aspiration, 37 cases were suspicious for malignancy or they were diagnosed as malignancies. All the thyroid nodules were taken for frozen section examination during surgery. On the frozen sections, 19 cases that were suspicious for malignant tumors underwent near total or total thyroidectomy along with central lymph node dissection, whereas 24 cases that were diagnosed as benign tumors underwent near total thyroidectomy or thyroid lobectomy. Based on the histopathological findings, 21 cases were diagnosed as Hashimoto’s thyroiditis associated with papillary cancer; the nodules of these 21 cases were on average 0.75 ㎝, Twenty two cases were diagnosed as Hashimoto’s thyroiditis associated with benign tumors, and the nodules of these cases measured on average 1.6 ㎝.
Conclusion: Hashimoto’s thyroiditis may present with a variety of clinical features, atypical ultrasonographic findings and a high false positive rate on fine needle aspiration. For the cases where Hashimoto’s thyroiditis is suspected before surgery, serum antibody tests, ultrasonography and fine needle aspiration should be performed for making the accurate diagnosis of Hashimoto’s thyroiditis. For the cases of suspicious malignant tumors, frozen section examination should be performed during surgery to decide on the correct operative procedure.
Methods: The authors retrospectively evaluated 43 patients who were diagnosed with Hashimoto’s thyroiditis after thyroidectomy between January 2001 and December 2006 at Chosun University Hospital.
Results: All patients underwent ultrasonography for the diagnosis of thyroid nodules. Ultrasonography revealed 16 calcified nodules with ill-defined margins, and these nodules were suspicious for malignancy. On performing preoperative fine needle aspiration, 37 cases were suspicious for malignancy or they were diagnosed as malignancies. All the thyroid nodules were taken for frozen section examination during surgery. On the frozen sections, 19 cases that were suspicious for malignant tumors underwent near total or total thyroidectomy along with central lymph node dissection, whereas 24 cases that were diagnosed as benign tumors underwent near total thyroidectomy or thyroid lobectomy. Based on the histopathological findings, 21 cases were diagnosed as Hashimoto’s thyroiditis associated with papillary cancer; the nodules of these 21 cases were on average 0.75 ㎝, Twenty two cases were diagnosed as Hashimoto’s thyroiditis associated with benign tumors, and the nodules of these cases measured on average 1.6 ㎝.
Conclusion: Hashimoto’s thyroiditis may present with a variety of clinical features, atypical ultrasonographic findings and a high false positive rate on fine needle aspiration. For the cases where Hashimoto’s thyroiditis is suspected before surgery, serum antibody tests, ultrasonography and fine needle aspiration should be performed for making the accurate diagnosis of Hashimoto’s thyroiditis. For the cases of suspicious malignant tumors, frozen section examination should be performed during surgery to decide on the correct operative procedure.
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REFERENCES
참고문헌 (28)
참고문헌 신청
1. [학술지(정기간행물)] - Hegedus L / 2001 / Thyroid ultrasound. Endocrinol metab / Clin North Am 30 : 339 ~ 360
2. [학술지(정기간행물)] - Cooper DS / 2006 / Management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 16 : 109 ~ 142
3. [학술지(정기간행물)] - Marqusee E / 2000 / Usefulness of ultrasonography in the management of nodular thyroid disease / Ann Intern Med 133 : 696 ~ 700
4. [학술지(정기간행물)] - Hagag P / 1998 / Role of ultrasound-guided fine- needle aspiration biopsy in evaluation of nonpalpable thyroid nodules / Thyroid 8 : 989 ~ 995
5. [학술지(정기간행물)] - Matsuzuka F / 1993 / Clinical aspects of primary thyroid lymphoma: Diagnosis and treatment based on our experience of 119 cases / Thyroid 3 : 93 ~ 99
2. [학술지(정기간행물)] - Cooper DS / 2006 / Management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 16 : 109 ~ 142
3. [학술지(정기간행물)] - Marqusee E / 2000 / Usefulness of ultrasonography in the management of nodular thyroid disease / Ann Intern Med 133 : 696 ~ 700
4. [학술지(정기간행물)] - Hagag P / 1998 / Role of ultrasound-guided fine- needle aspiration biopsy in evaluation of nonpalpable thyroid nodules / Thyroid 8 : 989 ~ 995
5. [학술지(정기간행물)] - Matsuzuka F / 1993 / Clinical aspects of primary thyroid lymphoma: Diagnosis and treatment based on our experience of 119 cases / Thyroid 3 : 93 ~ 99
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UCI(KEPA) : I410-ECN-0101-2013-514-002689963