지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.6
- 수록면
- 87 - 100 (14page)
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초록· 키워드
오류제보하기
Rifampicin is an acknowledged inhibitor of bacterial RNA polymerase. We observed that there exists a substantial variation in the basal-level tolerance to rifampicin across microbial species. A number of mechanisms have come to light which depict the molecular aspects of the behavior of an individual bacterial cell towards rifampicin. This review assesses the current knowledge about rifampicin and conjectures about the probable aspects of rifampicin which remain unexplored.
목차
Introduction
Major mechanisms of resistance to rifampicin
Variation in the tolerance to rifampicin across the microbial spectrum
Interference to the binding of rifampicin to RNA polymerase
Transcriptional response to rifampicin
Dealing with rifampicin as an antibiotic before becoming resistant to it
Unexplored facets of the character of rifampicin in nature
Conclusion
REFERENCES
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