Preoperative predictors of malignant gastric submucosal tumor

Ho Goon Kim; Seong Yeob Ryu; Sang Kwon Yun; Jae Kyoon Joo; Jae Hyuk Lee; Dong Yi Kim

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자료유형: 학술저널

저자정보: Ho Goon Kim (Chonnam National University Medical School) Seong Yeob Ryu (Chonnam National University Medical School) Sang Kwon Yun (Chonnam National University Medical School) Jae Kyoon Joo (Chonnam National University Medical School) Jae Hyuk Lee (Chonnam National University Medical School) Dong Yi Kim (Chonnam National University Medical School)

저널정보: 대한외과학회 Annals of Surgical Treatment and Research Journal of the Korean Surgical Society Vol.83 No.2

발행연도: 2012.8

수록면: 83 - 87 (5page)

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Purpose: The preoperative prediction of malignant potential in patients with gastric submucosal tumors (SMTs) plays an important role in decisions regarding their surgical management. Methods: We evaluated the predictors of malignant gastric SMTs in 314 patients with gastric SMTs who underwent surgery in Chonnam National University Hospital. Results: The malignant SMTs were significantly associated with age (odds ratio [OR], 1.067; 95% confidence interval [CI], 1.042 to 1.091; P ＜ 0.0001), presence of central ulceration (OR, 2.690; 95% CI, 1.224 to 5.909; P = 0.014), and tumor size (OR, 1.791; 95% CI, 1.483 to 2.164; P ＜ 0.0001). Receiver operating characteristic curve analysis showed that tumor size was a good predictor of malignant potential. The most relevant predictor of malignant gastric SMT was tumor size with cut-offs of 4.05 and 6.40 cm. Conclusion: Our findings indicated that age, central ulceration, and tumor size were significant preoperative predictors of malignant SMTs. We suggest that 4 cm be selected as a threshold value for malignant gastric SMTs. In patients with a gastric SMT larger than 4 cm with ulceration, wide resection of the full thickness of the gastric wall or gastrectomy with adequate margins should be performed because of its malignant potential.

#Stomach neoplasms #Submucosal tumor #Malignant factor #Preoperative predictor

참고문헌 (20)

참고문헌 신청

Campbell F / 1995 / Tumours of the oesophagus and stomach, In Diagnostic histopathology of tumours / Churchill Livingstone :193~242

Kempson RL / 1995 / Gastrointestinal stromal(smooth muscle) tumours, In Gastrointestinaland oesophageal pathology. 2nd ed / Churchill Livingstone :727~739

Chak A / 2002 / EUS in submucosal tumors / Gastrointest Endosc 56(4 Suppl):S43~S48

Connolly EM / 2003 / Gastrointestinal stromal tumours / Br J Surg 90:1178~1186

Brand B / 2002 / Impact of endoscopic ultrasound for evaluation of submucosal lesions in gastrointestinal tract / Dig Liver Dis 34:290~297