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논문 기본 정보

자료유형
학술저널
저자정보
Myung-Jin Lee (Gyeonggi-do Institute of Health & Environment) Woon-Ho Kim (Gyeonggi-do Institute of Health & Environmen) Han-Gil Cho (Gyeonggi-do Institute of Health & Environment) Sang-Seob Lee
저널정보
대한미생물학회 JOURNAL OF BACTERIOLOGY AND VIROLOGY JOURNAL OF BACTERIOLOGY AND VIROLOGY Vol.42 No.3
발행연도
2012.9
수록면
232 - 241 (10page)

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초록· 키워드

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In May 2011, five consecutive gastroenteritis outbreaks were reported at schools in Gyeonggi-do. Epidemiological inspection revealed that one food manufacture company provided "Kimchi", a traditional Korean side-dish, to these five schools for catering services. Fecal specimens were collected from students and food-handlers to determine causative viral agents. Norovirus genogroup GI was detected from 58 samples out of total 239 specimens by reverse-transcription (RT)-PCR, whereas norovirus GII was found only from one sample. Epidemiological studies also revealed that the Kimchi was processed using groundwater in the food manufacture company. Four groundwater samples were collected from the company and around the area. Norovirus GI was detected from three samples. To determine the norovirus genotypes of positive specimens from clinical and groundwater samples, sequencing and phylogenetic analyses were performed. The genogroup GI from 58 clinical and three groundwater samples and the GII from one food-handlerwere identified as norovirus GI.3 and GII.18, respectively. Sequence alignment analysis with norovirus GI.3 isolates revealed that identity between clinical and groundwater samples was over than 99.1% in nucleotide level. In conclusion, norovirus GI.3-contaminated groundwater caused the gastroenteritis outbreaks of five schools, through Kimchi. This molecular epidemiological study was an important report in Korea that clearly identified all transmission routes of norovirus GI.3.

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UCI(KEPA) : I410-ECN-0101-2014-475-001381026