지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.9
- 수록면
- 93 - 97 (5page)
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초록· 키워드
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Backgrounds/Aims: This study was designed to compare the recurrence patterns after curative hepatectomy, to compare the prognosis according to the initial site of metastasis, and to investigate the independent predictive factors associated with extrahepatic recurrence in hepatocellular carcinoma (HCC) patients after curative hepatectomy. Methods: From January 2000 to July 2009, 307 patients underwent curative hepatectomies for HCC at our institution; 152 patients showed recurrences. Patients were divided into 2 groups according to their initial recurrence site: the intrahepatic recurrence (IHR) group and extrahepatic recurrence (EHR) group. The IHR group was comprised of 111 patients and the EHR group was comprised of 41 patients. The study investigated the preoperative, intraoperative, and postoperative factors related to the recurrence pattern retrospectively and compared the prognoses of the patients. Results: A five-year survival rate after an initial recurrence was lower in the EHR group (21.5%) than the IHR group (36.3%) (p＜0.001). The preoperative alpha-fetoprotein (AFP) level was an independent risk factor for extrahepatic recurrence (p=0.014). Conclusions: Patients with a preoperative AFP level greater than 200 ng/ml have a higher incidence of extrahepatic metastases after a curative resection of HCC. Increased level of preoperative AFP is an indication for a short-term follow up hepatectomy.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (17)
참고문헌 신청
1. [학술지(정기간행물)] - Taura K / 2006 / Implication of frequent local ablation therapy for intrahepatic recurrence in prolonged survival of patients with hepatocellular carcinoma undergoing hepatic resection: an analysis of 610 patients over 16 years old / Ann Surg 244 : 265 ~ 273
2. [학술지(정기간행물)] - Sakata J / 2008 / Preoperative predictors of vascular invasion in hepatocellular carcinoma / Eur J Surg Oncol 34 : 900 ~ 905
3. [학술지(정기간행물)] - Belghiti J / 2002 / Resection of hepatocellular carcinoma: a European experience on 328 cases / Hepatogastroenterology 49 : 41 ~ 46
4. [학술지(정기간행물)] - Hanazaki K / 2000 / Survival and recurrence after hepatic resection of 386 consecutive patients with hepatocellular carcinoma / J Am Coll Surg 191 : 381 ~ 388
5. [학술지(정기간행물)] - Yang Y / 2007 / Patterns and clinicopathologic features of extrahepatic recurrence of hepatocellular carcinoma after curative resection / Surgery 141 : 196 ~ 202
2. [학술지(정기간행물)] - Sakata J / 2008 / Preoperative predictors of vascular invasion in hepatocellular carcinoma / Eur J Surg Oncol 34 : 900 ~ 905
3. [학술지(정기간행물)] - Belghiti J / 2002 / Resection of hepatocellular carcinoma: a European experience on 328 cases / Hepatogastroenterology 49 : 41 ~ 46
4. [학술지(정기간행물)] - Hanazaki K / 2000 / Survival and recurrence after hepatic resection of 386 consecutive patients with hepatocellular carcinoma / J Am Coll Surg 191 : 381 ~ 388
5. [학술지(정기간행물)] - Yang Y / 2007 / Patterns and clinicopathologic features of extrahepatic recurrence of hepatocellular carcinoma after curative resection / Surgery 141 : 196 ~ 202
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UCI(KEPA) : I410-ECN-0101-2014-514-001348678