지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.12
- 수록면
- 199 - 205 (7page)
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초록· 키워드
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Backgrounds/Aims: Surveillance programs and imaging modality developments have increased the detection rate of small hepatocellular carcinoma (HCC). In particular, liver transplantation produces good results and is now regarded an alternative to liver resection. However, optimal treatment for small HCC is still debated, and thus, the authors designed this study to document clinicopathological characteristics, to identify the prognostic factors of small HCC, and to determine the effectiveness of surgery. Methods: A total of 507 patients underwent curative liver resection for HCC between January 1996 and August 2006 in our institution. One hundred and thirty four of these patients with a single HCC of less than 3 cm and no gross vascular invasion were enrolled. Results: Major resection was performed in 32 (23.9%) patients; there was no postoperative mortality. Fifty-eight (43.3%) patients experienced recurrence, 53 developed intrahepatic recurrence alone, and 50 (94.3%) of 53 had tumors within the Milan criteria. Five-year disease-free and overall survival rates were 51.0% and 77.3%, respectively. Microscopic vascular invasion, positivity for hepatitis B surface antigen or antibody to hepatitis C, and an indocyanine green retention test at 15 minutes of more than 10% were found to be significantly correlated with disease-free overall survival. A platelet count of less than 100,000/mm3 was the only independent prognostic factors of overall survival identified. Conclusions: This study showed favorable outcome comparable to the survival after liver transplantation, thus that liver resection appears to be the primary treatment option for small HCC, even in cases with poor prognostic factors. (Korean J Hepatobiliary Pancreat Surg 2011;15:199-205)
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (31)
참고문헌 신청
1. [학술지(정기간행물)] - Zhang BH / 2004 / Randomized controlled trial of screening for hepatocellular carcinoma / J Cancer Res Clin Oncol 130 : 417 ~ 422
2. [학술지(정기간행물)] - Bruix J / 2005 / Practice Guidelines Committee, American Association for the Study of Liver Diseases. Management of hepatocellular carcinoma / Hepatology 42 : 1208 ~ 1236
3. [학술지(정기간행물)] - El-Serag HB / 2008 / Diagnosis and treatment of hepatocellular carcinoma / Gastroenterology 134 : 1752 ~ 1763
4. [학술지(정기간행물)] - Yamamoto J / 2001 / Treatment strategy for small hepatocellular carcinoma: comparison of long-term results after percutaneous ethanol injection therapy and surgical resection / Hepatology 34 : 707 ~ 713
5. [학술지(정기간행물)] - Jarnagin WR / 2010 / Management of small hepatocellular carcinoma: a review of transplantation, resection, and ablation / Ann Surg Oncol 17 : 1226 ~ 1233
2. [학술지(정기간행물)] - Bruix J / 2005 / Practice Guidelines Committee, American Association for the Study of Liver Diseases. Management of hepatocellular carcinoma / Hepatology 42 : 1208 ~ 1236
3. [학술지(정기간행물)] - El-Serag HB / 2008 / Diagnosis and treatment of hepatocellular carcinoma / Gastroenterology 134 : 1752 ~ 1763
4. [학술지(정기간행물)] - Yamamoto J / 2001 / Treatment strategy for small hepatocellular carcinoma: comparison of long-term results after percutaneous ethanol injection therapy and surgical resection / Hepatology 34 : 707 ~ 713
5. [학술지(정기간행물)] - Jarnagin WR / 2010 / Management of small hepatocellular carcinoma: a review of transplantation, resection, and ablation / Ann Surg Oncol 17 : 1226 ~ 1233
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UCI(KEPA) : I410-ECN-0101-2014-514-001273870