지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.9
- 수록면
- 152 - 156 (5page)
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초록· 키워드
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Backgrounds/Aims: To investigate survival rates and prognostic factors of patients with gallbladder cancer who were treated with surgery and postoperative radiation therapy. Methods: Seventeen gallbladder cancer patients who received surgery and postoperative radiotherapy from October 1989 to April 1998 were included in this retrospective study. Five patients had stage II, 8 patients had stage III, and 4 patients had stage IV disease according to the 1997 American Joint Committee on Cancer (AJCC) staging. All patients received ≥40 Gy of postoperative radiotherapy with a daily dose of 2.0 Gy/fraction and 15 patients received concurrent chemotherapy. An analysis was performed for the endpoints of overall and disease-free survival. Results: Of the 17 patients, 13 had no residual disease (R0), 1 had microscopic residual disease (R1), and 3 had macroscopic residual disease (R2) after surgery. Among patients with no residual disease, 4 had locoregional recurrences during the follow-up period. One patient with microscopic residual disease had local recurrence. The 5-year overall survival rate was 38.2%. The median overall survival time was 21 months and the median disease-free survival time was 12 months. Old age (≥60 years old), female gender, a high pathological stage (≥IVA), and the presence of residual disease after surgery were significant prognostic factors for disease-free survival. Conclusions: Despite a high proportion of patients with advanced disease and macroscopic residual disease, the prognosis of gallbladder patients who had postoperative radiotherapy is encouraging. Additional investigation to improve the loco-regional control of gallbladder cancer patients with adverse prognostic factors is warranted. (Korean J Hepatobiliary Pancreat Surg 2011;15:152-156)
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (9)
참고문헌 신청
1. [학술지(정기간행물)] - Duffy A / 2008 / Gallbladder cancer (GBC): 10-year experience at Memorial Sloan-Kettering Cancer Centre (MSKCC) / J Surg Oncol 98 : 485 ~ 489
2. [학술지(정기간행물)] - Mahantshetty UM / 2006 / Adjuvant radiation therapy in gall bladder cancers: 10 years experience at Tata Memorial Hospital / J Cancer Res Ther 2 : 52 ~ 56
3. [학술지(정기간행물)] - Gold DG / 2009 / Adjuvant therapy for gallbladder carcinoma: the Mayo Clinic Experience / Int J Radiat Oncol Biol Phys 75 : 150 ~ 155
4. [학술지(정기간행물)] - 박정익 / 2010 / 담낭암의 생존율에 영향을 미치는 예후 인자에 대한 분석 / 한국간담췌외과학회지 14 (3) : 173 ~ 183
5. [학술지(정기간행물)] - Czito BG / 2005 / Adjuvant external-beam radiotherapy with concurrent chemotherapy after resection of primary gallbladder carcinoma: a 23-year experience / Int J Radiat Oncol Biol Phys 62 : 1030 ~ 1034
2. [학술지(정기간행물)] - Mahantshetty UM / 2006 / Adjuvant radiation therapy in gall bladder cancers: 10 years experience at Tata Memorial Hospital / J Cancer Res Ther 2 : 52 ~ 56
3. [학술지(정기간행물)] - Gold DG / 2009 / Adjuvant therapy for gallbladder carcinoma: the Mayo Clinic Experience / Int J Radiat Oncol Biol Phys 75 : 150 ~ 155
4. [학술지(정기간행물)] - 박정익 / 2010 / 담낭암의 생존율에 영향을 미치는 예후 인자에 대한 분석 / 한국간담췌외과학회지 14 (3) : 173 ~ 183
5. [학술지(정기간행물)] - Czito BG / 2005 / Adjuvant external-beam radiotherapy with concurrent chemotherapy after resection of primary gallbladder carcinoma: a 23-year experience / Int J Radiat Oncol Biol Phys 62 : 1030 ~ 1034
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UCI(KEPA) : I410-ECN-0101-2014-514-001274362