지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.3
- 수록면
- 35 - 41 (7page)
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초록· 키워드
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Purpose: We evaluated the effect of adjuvant radiotherapy on survival in patients who underwent curative resection for gallbladder cancer with lymph node metastasis.
Methods: Among the patients underwent curative resection even though there was lymph node metastasis; fifteen patients underwent adjuvant radiotherapy with over 40 Gy (RTx group) and 10 patients did not (no RTx group). We compared these two groups retrospectively.
Results: The median disease free survival (DFS) of the RTx group (21.6 months) was longer than for the no RTx group (6.6 months, p=0.451). The median overall survival (OS) of the RTx group (30.5 months) was also longer than the no RTx group (14.2 months). One-, 2-, and 5-yr OS rates were 60.0%, 40.0% and 40.0% in the no RTx group, and 86.7%, 70.9% and 26.6% in the RTx group, respectively (p=0.507). Five patients developed recurrence within 1 year (50.0%) in the no RTx group; there were 3 (20.0%) in the RTx group.
Conclusion: Our study was limited by its retrospective nature and small numbers of patients. However, it suggests that adjuvant radiotherapy might improve DFS and OS for patients with completely resected but lymph node metastasized gallbladder cancer. Also this therapy seems to delay time to postoperative recurrence.
Methods: Among the patients underwent curative resection even though there was lymph node metastasis; fifteen patients underwent adjuvant radiotherapy with over 40 Gy (RTx group) and 10 patients did not (no RTx group). We compared these two groups retrospectively.
Results: The median disease free survival (DFS) of the RTx group (21.6 months) was longer than for the no RTx group (6.6 months, p=0.451). The median overall survival (OS) of the RTx group (30.5 months) was also longer than the no RTx group (14.2 months). One-, 2-, and 5-yr OS rates were 60.0%, 40.0% and 40.0% in the no RTx group, and 86.7%, 70.9% and 26.6% in the RTx group, respectively (p=0.507). Five patients developed recurrence within 1 year (50.0%) in the no RTx group; there were 3 (20.0%) in the RTx group.
Conclusion: Our study was limited by its retrospective nature and small numbers of patients. However, it suggests that adjuvant radiotherapy might improve DFS and OS for patients with completely resected but lymph node metastasized gallbladder cancer. Also this therapy seems to delay time to postoperative recurrence.
목차
Introduction
Methods
Results
Discussion
Conclusion
References
참고문헌 (23)
참고문헌 신청
1. [학술지(정기간행물)] - Gourgiotis S / 2008 / Gallbladder cancer / Am J Surg 196 : 252 ~ 264
2. [학술지(정기간행물)] - Reid KM / 2007 / Diagnosis and surgical management of gallbladder cancer: a review / J Gastrointest Surg 11 : 671 ~ 681
3. [학술지(정기간행물)] - Duffy A / 2008 / Gallbladder cancer (GBC): 10-year experience at Memorial Sloan-Kettering Cancer Centre (MSKCC) / J Surg Oncol 98 : 485 ~ 489
4. [학술지(정기간행물)] - Mahantshetty UM / 2006 / Adjuvant radiation therapy in gall bladder cancers: 10 years experience at Tata Memorial Hospital / J Cancer Res Ther 2 : 52 ~ 56
5. [학술지(정기간행물)] - Kresl JJ / 2002 / Adjuvant external beam radiation therapy with concurrent chemotherapy in the management of gallbladder carcinoma / Int J Radiat Oncol Biol Phys 52 : 167 ~ 175
2. [학술지(정기간행물)] - Reid KM / 2007 / Diagnosis and surgical management of gallbladder cancer: a review / J Gastrointest Surg 11 : 671 ~ 681
3. [학술지(정기간행물)] - Duffy A / 2008 / Gallbladder cancer (GBC): 10-year experience at Memorial Sloan-Kettering Cancer Centre (MSKCC) / J Surg Oncol 98 : 485 ~ 489
4. [학술지(정기간행물)] - Mahantshetty UM / 2006 / Adjuvant radiation therapy in gall bladder cancers: 10 years experience at Tata Memorial Hospital / J Cancer Res Ther 2 : 52 ~ 56
5. [학술지(정기간행물)] - Kresl JJ / 2002 / Adjuvant external beam radiation therapy with concurrent chemotherapy in the management of gallbladder carcinoma / Int J Radiat Oncol Biol Phys 52 : 167 ~ 175
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UCI(KEPA) : I410-ECN-0101-2014-514-001274599