지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.3
- 수록면
- 42 - 49 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: This study was designed to analyze the prognosis following segmental bile duct resection (BDR) versus pancreatoduodenectomy (PD) for mid bile duct (mBD) cancer.
Methods: During the 4 years between 2003 and 2006, 55 patients underwent surgical resection for mBD cancer in our institution. Medical records were reviewed retrospectively. They were divided into two groups, a BDR group (n=24) and a PD group (n=31) according to the extent of resection.
Results: Median follow-up was 43 months. Overall 3- and 5-year survival rates were 56.0% and 33.8%, respectively. The BDR group had lower tumor stages than the PD group (p=0.011). R0 resection was achieved in 17 (70.8%) of the BDR group and 30 (96.8%) of the PD group. Median survival periods were 43 and 34 months after R0 and R1 resections, respectively (p=0.715). Recurrence occurred in 41 patients after a mean period of 18 months. Three- and 5-year survival rates were 62.5% and 27.2% after BDR, respectively, and 51.5% and 34% after PD, respectively (p=0.715). No significant risk factors for shorter patient survival times was identified. Aggressive treatment of recurrence did not appear to prolong patient survival.
Conclusion: The extent of resection for mBD cancer did not affect the survival outcome when R0 resection was achieved. Considering the operative risk in patients with older ages or co-morbidities, PD should be considered only after obtainment of simultaneous tumor-free radial and proximal longitudinal resection margins.
Methods: During the 4 years between 2003 and 2006, 55 patients underwent surgical resection for mBD cancer in our institution. Medical records were reviewed retrospectively. They were divided into two groups, a BDR group (n=24) and a PD group (n=31) according to the extent of resection.
Results: Median follow-up was 43 months. Overall 3- and 5-year survival rates were 56.0% and 33.8%, respectively. The BDR group had lower tumor stages than the PD group (p=0.011). R0 resection was achieved in 17 (70.8%) of the BDR group and 30 (96.8%) of the PD group. Median survival periods were 43 and 34 months after R0 and R1 resections, respectively (p=0.715). Recurrence occurred in 41 patients after a mean period of 18 months. Three- and 5-year survival rates were 62.5% and 27.2% after BDR, respectively, and 51.5% and 34% after PD, respectively (p=0.715). No significant risk factors for shorter patient survival times was identified. Aggressive treatment of recurrence did not appear to prolong patient survival.
Conclusion: The extent of resection for mBD cancer did not affect the survival outcome when R0 resection was achieved. Considering the operative risk in patients with older ages or co-morbidities, PD should be considered only after obtainment of simultaneous tumor-free radial and proximal longitudinal resection margins.
목차
서론
방법
결과
고찰
결론
참고문헌
참고문헌 (16)
참고문헌 신청
1. [학술지(정기간행물)] - Jang JY / 2005 / Actual long-term outcome of extrahepatic bile duct cancer after surgical resection / Ann Surg 241 : 77 ~ 84
2. [학술지(정기간행물)] - Chamberlain RS / 2000 / Hilar cholangiocarcinoma: a review and commentary / Ann Surg Oncol 7 : 56 ~ 66
3. [학술지(정기간행물)] - Nagorney DM / 1993 / Outcomes after curative resections of cholangiocarcinoma / Arch Surg 128 : 871 ~ 877
4. [학술지(정기간행물)] - Klempnauer J / 1997 / Resectional surgery of hilar cholangiocarcinoma: a multivariate analysis of prognostic factors / J Clin Oncol 15 : 947 ~ 954
5. [학술지(정기간행물)] - Pichlmayr R / 1996 / Surgical treatment in proximal bile duct cancer. A single-center experience / Ann Surg 224 : 628 ~ 638
2. [학술지(정기간행물)] - Chamberlain RS / 2000 / Hilar cholangiocarcinoma: a review and commentary / Ann Surg Oncol 7 : 56 ~ 66
3. [학술지(정기간행물)] - Nagorney DM / 1993 / Outcomes after curative resections of cholangiocarcinoma / Arch Surg 128 : 871 ~ 877
4. [학술지(정기간행물)] - Klempnauer J / 1997 / Resectional surgery of hilar cholangiocarcinoma: a multivariate analysis of prognostic factors / J Clin Oncol 15 : 947 ~ 954
5. [학술지(정기간행물)] - Pichlmayr R / 1996 / Surgical treatment in proximal bile duct cancer. A single-center experience / Ann Surg 224 : 628 ~ 638
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2014-514-001274600