국소형 췌소도세포증(Nesidioblastosis) 1예

강봉수; 강성일; 구혜영; 이성배; 강혜윤; 박석원; 정철운

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자료유형: 학술저널

저자정보: 강봉수 (포천중문대학교) 강성일 (포천중문대학교) 구혜영 (포천중문대학교) 이성배 (포천중문대학교) 강혜윤 (포천중문대학교) 박석원 (포천중문대학교) 정철운 (포천중문대학교)

저널정보: 한국간담췌외과학회 Annals of Hepato-Biliary-Pancreatic Surgery 한국간담췌외과학회지 제12권 제4호

발행연도: 2008.12

수록면: 302 - 306 (5page)

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Nesidioblastosis is a rare disorder, and it usually considered as a cause of neonatal hyperinsulinemic hypoglycemia. A 35 year-old-woman with hyperinsulinemic hypoglycemia was admitted in an unconscious condition. Abdominal CT, pancreas MRI and celiac angiography with an intra-arterial calcium stimulation test revealed a suspicious insulin-producing tumorous lesion in the head of pancreas. The patient underwent enucleation of the pancreas head tumor under the initial diagnosis of insulinoma. However, the tumor was confirmed histologically as nesidioblastosis that showed ductoendocrine proliferations and numerous small endocrine cell groups. Nesidioblastosis is classified into a focal type and a diffuse type, which are characterized by different clinical outcomes. The patient in our case showed a normal blood glucose level after operation, which is often the case for the focal type. Herein, we report this very rare case of adult nesiodioblastosis that was successfully treated by surgical resection.

#Nesidioblastosis #Hyperinsulinemia #Hypoglycemia #Surgery #췌소도세포증 #고인슐린혈증 #저혈당증 #수술

참고문헌 (18)

참고문헌 신청

1. [학술지(정기간행물)] - Laidlaw GF / 1938 / Nesidioblastoma, the islet cell tumor of the pancreas / Am J Pathol 14 : 125 ~ 134

2. [학술지(정기간행물)] - de Lonlay-Debeney P / 1999 / Clinical features of 52 neonates with hyperinsulinism / N Engl J Med 340 (15) : 1169 ~ 1175

3. [학술지(정기간행물)] - van der Wal BC / 2000 / Adult hyperinsulinemic hypoglycemia not caused by an insulinoma: a report of two cases / Virchows Arch 2000 (5) : 481 ~ 486

4. [학술지(정기간행물)] - Raffel A / 2007 / Diffuse nesidioblastosis as a cause of hyperinsulinemic hypoglycemia in adults: A diagnostic and therapeutic challenge / Surgery 141 : 185 ~ 186

5. [학술지(정기간행물)] - 김철남 / 2004 / 고인슐린혈성 저혈당을 보인 성인에서의 췌소도세포증 / 한국간담췌외과학회지 8 (3) : 202 ~ 205

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