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논문 기본 정보

자료유형
학술저널
저자정보
Yoo-Hun Noh (Chung-Ang University) Do-Hee Kim (BioGrand) Joon Yub Kim (Chung-Ang University) Jiae Park (Chung-Ang University) Ok Hyeon Kim (Chung-Ang University) Daeseok Han (Korea Food Research Institute) Won-Yong Kim (Chung-Ang University) Sung-Su Kim (Chung-Ang University) Moo-Yeol Lee (Chung-Ang University) Seok-Hyun Heo (Korea Health Supplements Institute) Misook Kim (Dankook University) Won Bok Lee (Chung-Ang University) Yoonhwa Jeong (Dankook University) Soon Chul Myung (Chung-Ang University)
저널정보
한국영양학회 Nutrition Research and Practice Nutrition Research and Practice Vol.6 No.6
발행연도
2012.12
수록면
505 - 512 (8page)

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Many aging male suffer various andropause symptoms including loss of physical and mental activities. This study evaluated the putative alleviative effects of CRS-10 dandelion and rooibos extract complex (CRS-10) on the symptoms of andropause. The survival rate of TM3 Leydig cells (TM3 cells) treated with CRS-10 was measured based on typical physiological stress. After daily intake of CRS-10 for 4 weeks, the level of testosterone, physical activity and both the number and activity of sperm in older rats (18 weeks) were measured. Furthermore, thirty males were surveyed with AMS (Aging Males" Symptoms) questionnaire after intake of 400 mg of CRS-10. Overall, CRS-10 protected TM3 cells from serum restriction and oxidative stress via activation of ERK and Akt pathways. The level of testosterone and activation of spermatogenesis in rats were significantly enhanced. In addition, physical locomotion was markedly improved. Daily intake of 400 mg of CRS-10 improved the quality of life among agingmale respondents, according to a clinical survey using the AMS. The results indicate the potential of CRS-10 as a safe and efficacious natural substance for reducing or alleviating andropause symptoms.

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Abstract
Introduction
Materials and Methods
Results
Discussion
References

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UCI(KEPA) : I410-ECN-0101-2014-594-000594394