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논문 기본 정보

자료유형
학술저널
저자정보
김수연 (부산대학교병원) 문은수 (부산대학교병원) 박제민 (부산대학교병원) 이병대 (부산대학교병원) 이영민 (부산대학교병원) 정영인 (부산대학교) 하지경 (부산대학교병원)
저널정보
대한생물치료정신의학회 생물치료정신의학 생물치료정신의학 제18권 제2호
발행연도
2012.12
수록면
201 - 208 (8page)

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Objectives:Dropout is one of the important factors that may hinder successful treatment in the maintenance treatment of bipolar disorder. Dropout rates of bipolar patients have been reported in 32-51%, but there are lack of evidences about risk factors of dropout in bipolar I patients with the first manic or mixed episode. The aim of this study was to investigate the dropout rate and risk factors of dropout in bipolar I patients with the first manic or mixed episode.
Method:Fifty eight bipolar I patients with the first manic or mixed episode were included in this study. We examined sociodemographic and clinical variables that may be associated with dropout by chart review retrospectively. Dropout for 2 year maintenance treatment was assessed by telephone interview. Cox proportional hazards regression model was used to assess risk factors affecting the time to dropout.
Results:Dropout rate for 2 years in the maintenance treatment of bipolar I patients was 49.8%. Lower socioeconomic status, past impulsive behaviors, and lack of familial support for treatment were significantly associated with time to dropout in bipolar I patients.
Conclusion:Dropout rates of bipolar patients with the first manic or mixed episode were high, and these were associated with socioeconomic status, impulsivity, and familial support. For the successful treatment of bipolar disorder patients, it is necessary to detect the high risk group of dropout and do psychosocial treatments in order to reduce dropout. Large-scaled, multicenter, and prospective studies are needed to confirm these results in the near future.

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UCI(KEPA) : I410-ECN-0101-2014-513-000468549