지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.12
- 수록면
- 368 - 371 (4page)
이용수
초록· 키워드
오류제보하기
The pathogenicity of influenza A viruses is a multigenic trait, which is orchestrated by the global networks between eight viral genomic constituents and their cellular interacting partners. A recent report provided information on the finding of a new PA ribosomal frameshifting product, the PA-X protein, in the influenza A virus segment 3, and an endonuclease property was suggested for a possible role of the PA-X protein. In cultured cells, viral growth was not affected by the PA-X protein expression. However, the reduced pathogenicity of mice appeared to be closely associated with the PA-X protein expression. It was also revealed that the PA-X protein was able to modulate host gene expression. Considered together, the PA-X protein can be a cellular signaling modulator and subsequently control viral pathogenicity. By reviewing recent publications, we present new insights in the contribution of the PA-X protein to the cellular signaling network and the resultant viral pathogenicity.
목차
서론
결론
참고문헌
참고문헌 (0)
참고문헌 신청이 논문의 저자 정보
이 논문과 함께 이용한 논문
Cell Culture-based Influenza Vaccines as Alternatives to Egg-based Vaccines
Ilseob Lee
,
Jin Il Kim
,
Man-Seong Pa
외 1명
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2013
.03
Detection of Influenza A Virus by Interdigitated Nanogap Devices
Jimin Pa
,
k
,
Dae Keun Pa
외 4명
한국진공학회 학술발표회초록집
2014
.02
RNA Granules and Stress Granules in Virus Systems
Kyongmin Kim
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2012
.09
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2014-475-000463207