지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Backgrounds: Danggui, one of the major herbs in Korean traditional medicine consists of three species: Angelica gigas of Korea, Angelica sinensis of China, and Angelica acutiloba of Japan. Despite its importance in Korean traditional medicine, recognition of the clinical differences between its three species is insufficient.
Objectives: The purpose of the present review is to suggest evidence in using Angelica gigas, Angelica sinensis, and Angelica acutiloba distinctively in clinic, by comparing their pharmacological effects and bioactive compounds.
Methods: We searched articles published from 2000 to 2009 in Pubmed, EMbase, and RISS. The search keywords were “Angelica gigas”, “Angelica sinensis”, “Angelica acutiloba”, “dongquei”, “toki”, “Angelicae Radix”, “Archangelica officinalis Hoffm.”, “Garden Angelica”, “Chinese angelica root”, “tangkuei”, and “danggui”. 861 articles were searched. Among them, we selected 143 articles which met our inclusion criteria.
Results: This review summarizes active constituents, experimental studies, clinical studies, pharmacokinetics, side effects and toxicity, drug interaction, and industrial use of Angelica gigas, Angelica sinensis, and Angelica acutiloba.
Conclusions: While Angelica sinensis and Angelica acutiloba are relatively similar, Angelica gigas is quite different from the others in main active constituents and genetic form. The main experimental studies of Danggui are cardiovascular studies, central nervous system studies and anti-cancer activity. Even though there were cases in which the three species show similar pharmacological effects, the mechanism was not always shared. Therefore, distinguished use of Angelica gigas, Angelica sinensis and Angelica acutiloba is needed.
Objectives: The purpose of the present review is to suggest evidence in using Angelica gigas, Angelica sinensis, and Angelica acutiloba distinctively in clinic, by comparing their pharmacological effects and bioactive compounds.
Methods: We searched articles published from 2000 to 2009 in Pubmed, EMbase, and RISS. The search keywords were “Angelica gigas”, “Angelica sinensis”, “Angelica acutiloba”, “dongquei”, “toki”, “Angelicae Radix”, “Archangelica officinalis Hoffm.”, “Garden Angelica”, “Chinese angelica root”, “tangkuei”, and “danggui”. 861 articles were searched. Among them, we selected 143 articles which met our inclusion criteria.
Results: This review summarizes active constituents, experimental studies, clinical studies, pharmacokinetics, side effects and toxicity, drug interaction, and industrial use of Angelica gigas, Angelica sinensis, and Angelica acutiloba.
Conclusions: While Angelica sinensis and Angelica acutiloba are relatively similar, Angelica gigas is quite different from the others in main active constituents and genetic form. The main experimental studies of Danggui are cardiovascular studies, central nervous system studies and anti-cancer activity. Even though there were cases in which the three species show similar pharmacological effects, the mechanism was not always shared. Therefore, distinguished use of Angelica gigas, Angelica sinensis and Angelica acutiloba is needed.
목차
서론
연구 방법
결과
고찰
결론
참고문헌
참고문헌 (147)
참고문헌 신청
1. [단행본] - 전국한의과대학 공동교재편찬위원회 / 2004 / 본초학 / 영림사 : 629 ~ 631
2. [단행본] - 황도연 / 2004 / 方藥合編 / 남산당 : 147 ~
3. [단행본] - 주영승 / 2002 / 耘谷 本草學: 總論 / 서림재 : 377 ~ 391
4. [단행본] - 주영승 / 2002 / 耘谷 本草學: 各論 下 / 서림재 : 448 ~
5. [학술지(정기간행물)] - / 2007 / Angelan isolated from Angelica gigas Nakai induces dendritic cell maturation through toll-like receptor 4 / INTERNATIONAL IMMUNOPHARMACOLOGY 7 : 78 ~ 87
2. [단행본] - 황도연 / 2004 / 方藥合編 / 남산당 : 147 ~
3. [단행본] - 주영승 / 2002 / 耘谷 本草學: 總論 / 서림재 : 377 ~ 391
4. [단행본] - 주영승 / 2002 / 耘谷 本草學: 各論 下 / 서림재 : 448 ~
5. [학술지(정기간행물)] - / 2007 / Angelan isolated from Angelica gigas Nakai induces dendritic cell maturation through toll-like receptor 4 / INTERNATIONAL IMMUNOPHARMACOLOGY 7 : 78 ~ 87
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UCI(KEPA) : I410-ECN-0101-2014-519-000281048