지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Glycyrrhetinic acid, which is a component of licorice, can cause hypermineralocorticoidism through the inhibition of 11β-hydroxysteroid dehydrogenase. So, a high dose intake of licorice can lead to hypermineralocorticoidism with potassium loss and depression of the renin-angiotensin-aldosterone system.
We report a 73-year-old man with muscle weakness of proximal lower limbs with hypokalemia (Serum K＋: 1.4 mEq/L) due to taking self-prescribed licorice without OMD’s diagnosis. He boiled 60~100g licorice / day in water and drank it intermittently for 1 month due to arthralgia and swelling of both his knees. Patient’s serum renin activity and aldosterone level were far beyond the normal range. He also had metabolic alkalosis with pH 7.552. After quitting the licorice, hypokalemia and muscle weakness of proximal lower limbs gradually improved within 1week.
We report a 73-year-old man with muscle weakness of proximal lower limbs with hypokalemia (Serum K＋: 1.4 mEq/L) due to taking self-prescribed licorice without OMD’s diagnosis. He boiled 60~100g licorice / day in water and drank it intermittently for 1 month due to arthralgia and swelling of both his knees. Patient’s serum renin activity and aldosterone level were far beyond the normal range. He also had metabolic alkalosis with pH 7.552. After quitting the licorice, hypokalemia and muscle weakness of proximal lower limbs gradually improved within 1week.
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고찰 및 결론
참고문헌
참고문헌 (9)
참고문헌 신청
1. [단행본] - 허준 / 2005 / 동의보감 / 동의보감 출판사 : 2146 ~
2. [학술지(정기간행물)] - Cayley FE / 1950 / Potassium deficiency in p-aminosalicylic acid therapy: cardiac and paralytic effects / Lancet 1 : 447 ~ 448
3. [학술지(정기간행물)] - 조숙경 / 2001 / 감초로 유발된 저칼륨혈증 / Kidney Research and Clinical Practice 20 (6) : 1021 ~ 1025
4. [학술지(정기간행물)] - 홍현일 / 2005 / 감초 복용에 의한 저칼륨마비와 횡문근융해가 병발한 1예 / 대한내분비학회지 20 (2) : 179 ~ 182
5. [학술지(정기간행물)] - 김범준 / 2006 / 감초 유발성 저칼륨혈증성 근육병증 1예 / 대한신경과학회지 24 (4) : 389 ~ 391
2. [학술지(정기간행물)] - Cayley FE / 1950 / Potassium deficiency in p-aminosalicylic acid therapy: cardiac and paralytic effects / Lancet 1 : 447 ~ 448
3. [학술지(정기간행물)] - 조숙경 / 2001 / 감초로 유발된 저칼륨혈증 / Kidney Research and Clinical Practice 20 (6) : 1021 ~ 1025
4. [학술지(정기간행물)] - 홍현일 / 2005 / 감초 복용에 의한 저칼륨마비와 횡문근융해가 병발한 1예 / 대한내분비학회지 20 (2) : 179 ~ 182
5. [학술지(정기간행물)] - 김범준 / 2006 / 감초 유발성 저칼륨혈증성 근육병증 1예 / 대한신경과학회지 24 (4) : 389 ~ 391
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UCI(KEPA) : I410-ECN-0101-2014-519-000262372