지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2012.11
- 수록면
- 2,620 - 2,623 (4page)
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초록· 키워드
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Recent experimental observations support the hypothesis that mechanical stimuli play a role in regulating specialized molecules expression in articular cartilage in vitro and in vivo. These specific molecules might be induced by the initiation of relative motion between the articular cartilage surfaces. Other studies have demonstrated that the continuous passive motion(CPM) bioreactor for whole joint can provides a platform for possible future in vitro studies and applications including possible interactions of bio-mechanical and biochemical signals. This system consists of a joint culture chamber and a CPM-like stimulation device. To achieve this, we fabricated a human knee joint model using CAD/CAM technology and developed the culture system for regeneraton of articular cartilage. Also, we developed the movement system based on a CPM device for mimicked the human knee joint movement. In this study, we will develop an intelligent and bio-mimetic bioreactor system for regeneration of defected articular cartilage. Then, this system could be used to investigate the effects of rehabilitative joint motion in dynamic culture.
목차
Abstract
1. 서론
2. 무릎관절형상을 이용한 배양시스템
3. CPM 장치 기반 구동시스템 설계
4. 결론
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UCI(KEPA) : I410-ECN-0101-2014-550-000183993