지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.12
- 수록면
- 809 - 816 (8page)
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초록· 키워드
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Both obesity and menopause cause the dysfunction of autonomic nervous system. Recent human studies have reported that exercise pressor reflex (EPR)-mediated increases in blood pressure are exaggerated in obese or postmenopausal women. Whether these findings can be extended to both obese and postmenopausal women remains unclear. Mean arterial pressure (MAP), cardiac output (CO), and total vascular conductances (TVC) were measured in normal premenopausal women (NPW; n = 11; 36 ± 2 yr), normal postmenopausal women (NPOW; n = 14; 57 ± 1 yr), and overweight postmenopausal women (OPOW; n = 14; 56 ± 1 yr) at baseline, and during static handgrip at 50% maximal voluntary contraction (MVC) followed by a period of postexercise muscular ischemia (PEMI) to isolate the metabolic component of the EPR. Changes in MAP from baseline were augmented in OPOW subjects during both 50% MVC handgrip (P < 0.05), and these group differences were maintained during PEI (P < 0.05). There were no differences in heart rate (HR), stroke volume (SV), and CO during hand grip exercise and PEMI among groups. Even though there was no group difference in TVC during exercise and PEMI, the TVC tended to be abolished in OPOW group. In summary, compared with NPW subjects, OPOW group exhibit exaggerated pressor responses to handgrip exercise that are maintained during PEMI, indicating that activation of the metabolic component of the EPR is augmented in OPOW group. The exaggerated pressor response mediated by the muscle metaboreflex activation in OPOW group mainly occurs via preperial vasoconstriction with little change in CO.
목차
Abstract
1. 서론
2. 연구 방법
3. 결과
4. 논의
5. 결론
인용문헌
참고문헌 (24)
참고문헌 신청
1. [학술지(정기간행물)] - Burger, J. P. W. / 2009 / Blood pressure response to moderate physical activity is increased on obesity / Neth. J. Med. 67 : 342 ~ 346
2. [학술지(정기간행물)] - Delaney, E. P. / 2010 / Exaggerated sympathetic and pressor responses to handgrip exercise in older hypertensive humans : role of the muscle metaboreflex / Am. J. Physiol. Heart Circul. Physiol. 299 : H1318 ~ H1327
3. [학술지(정기간행물)] - Dicarlo, S. E. / 1992 / Onset of exercise shifts operating point of arterial baroreflex to higher pressures / Am. J. Appl. Physiol. 262 : 303 ~ 307
4. [학술지(정기간행물)] - Ettinger, S. M. / 1998 / Effects of the ovarian cycle on sympathetic neural outflow during static exercise / J. Appl. Physiol. 85 : 2075 ~ 2081
5. [학술지(정기간행물)] - Harrison-Bernard L. M. / 2000 / Postmenopausal hypertension / Curr. Hypertens. Rep. 2 : 202 ~ 207
2. [학술지(정기간행물)] - Delaney, E. P. / 2010 / Exaggerated sympathetic and pressor responses to handgrip exercise in older hypertensive humans : role of the muscle metaboreflex / Am. J. Physiol. Heart Circul. Physiol. 299 : H1318 ~ H1327
3. [학술지(정기간행물)] - Dicarlo, S. E. / 1992 / Onset of exercise shifts operating point of arterial baroreflex to higher pressures / Am. J. Appl. Physiol. 262 : 303 ~ 307
4. [학술지(정기간행물)] - Ettinger, S. M. / 1998 / Effects of the ovarian cycle on sympathetic neural outflow during static exercise / J. Appl. Physiol. 85 : 2075 ~ 2081
5. [학술지(정기간행물)] - Harrison-Bernard L. M. / 2000 / Postmenopausal hypertension / Curr. Hypertens. Rep. 2 : 202 ~ 207
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UCI(KEPA) : I410-ECN-0101-2014-500-002376001