지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.3
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- 1 - 6 (6page)
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The aim of this study was to investigate food intake, serum leptin levels, and leptin mRNA expression during the sexual cycle in rats. Female Wistar?Imamichi rats aged 8-10 weeks were used in this experiment. Food intake was measured during the light and dark phases (light on at 07:00 and off at 19:00) of the 4-day estrous cycle in female rats. Serum leptin levels were measured by ELISA, and leptin mRNA expression levels were analyzed using real-time PCR on diestrous- and proestrous-stage rats. Our results revealed that during the sexual cycle, food intake was significantly higher in the dark phase compared with the light phase. Food intake in proestrous females was significantly lower in the light and dark phases compared with the other groups. Serum leptin concentrations were significantly higher in both phases in proestrous rats compared with diestrous rats. There was a significant increase in leptin mRNA expression in adipose tissue during the proestrous period compared with the diestrous period. These findings suggest that increased leptin mRNA expression and serum leptin levels, which are induced by estrogen during the proestrous stage, may play a role in regulating appetitive behavior.
목차
Materials and Methods
Results
Discussion
References
참고문헌 (24)
참고문헌 신청
1. [학술지(정기간행물)] - Sjoholm K / 2006 / Hypothalamic response to leptin changes during a hormonally induced estrous cycle in rats / Cent Eur J Biol 1 : 221 ~ 234
2. [학술지(정기간행물)] - Schneider JE / 2004 / Energy balance and reproduction / Physiol Behav 81 : 289 ~ 317
3. [학술지(정기간행물)] - Gray JM / 1981 / Food intake, body weight, and adiposity in female rats: actions and interactions of progestins and antiestrogens / Am J Physiol 240 (5) : 474 ~ 481
4. [학술지(정기간행물)] - Wade GN / 1993 / Tamoxifen mimics the effects of estradiol on food intake, body weight, and body composition in rats / Am J Physiol 264 : 1219 ~ 1223
5. [학술지(정기간행물)] - Tritos NA / 2004 / Estradiol-induced anorexia is independent of leptin and melaninconcentrating hormone / Obes Res 12 (4) : 716 ~ 724
2. [학술지(정기간행물)] - Schneider JE / 2004 / Energy balance and reproduction / Physiol Behav 81 : 289 ~ 317
3. [학술지(정기간행물)] - Gray JM / 1981 / Food intake, body weight, and adiposity in female rats: actions and interactions of progestins and antiestrogens / Am J Physiol 240 (5) : 474 ~ 481
4. [학술지(정기간행물)] - Wade GN / 1993 / Tamoxifen mimics the effects of estradiol on food intake, body weight, and body composition in rats / Am J Physiol 264 : 1219 ~ 1223
5. [학술지(정기간행물)] - Tritos NA / 2004 / Estradiol-induced anorexia is independent of leptin and melaninconcentrating hormone / Obes Res 12 (4) : 716 ~ 724
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UCI(KEPA) : I410-ECN-0101-2014-560-003007709