The Thermophysical properties of thermal conductivity, viscosity, and heat capacity for CO₂ slurry (CO₂ gas and CO₂-hydrate mixture) having a high gas phase volume fraction were predicted using the conventional mixture models and the TRAPP model under hydrate formation conditions. Based on the calculated thermophysical properties, the heat transfer coefficient and pressure drop of the CO2 slurry in the tube were predicted. The thermal conductivity of CO₂ slurry ranged from 0.02 to 0.2 W/m-K, and the mixture viscosity was larger than that of pure CO₂ by 1.9~2.7 times. The heat capacity of CO₂ slurry ranged from 63 to 68% of that for pure CO₂. The predicted heat transfer coefficient of CO2 slurry was 6 times higher than that of pure CO₂. In the separate model, the estimated pressure drop increased with an increase of CO₂-hydrate mole fraction, and was 60% of that of pure CO₂.