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자료유형
학술저널
저자정보
Hyeong-Kyu Jeon (Chungbuk National University School of Medicine) Dongmin Lee (Chungbuk National University School of Medicine) Hansol Park (Chungbuk National University School of Medicine) Duk-Young Min (Eulji University School of Medicine) Han-Jong Rim (Korea University College of Medicine) Hongman Zhang (Guangxi Center for Disease Prevention and Control) Yichao Yang (Guangxi Center for Disease Prevention and Control) Xueming Li (Guangxi Center for Disease Prevention and Control) Keeseon S Eom (Chungbuk National University School of Medicine)
저널정보
대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.50 No.4
발행연도
2012.12
수록면
391 - 394 (4page)

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The prevalence of liver and intestinal fluke infections was determined by surveying inhabitants of Hengxuan, Fusui, and Shanglin villages which were known to be endemic for liver flukes in Guangxi, China in May 2010. A total of 718 people were examined for helminth eggs by the Kato-Katz thick smear technique, ultrasonography, immunoaffinity chromatography, and DNA sequencing. The overall egg positive rate was found to be 59.6% (28.0-70.6%) that included mixed infections with liver and intestinal flukes. Cases showing higher than 20,000 eggs per gram of feces (EPG) were detected between 1.3% and 16.2%. Ultrasonographic findings exhibited overall 28.2% (72 of 255 cases) dilatation rate of the intrahepatic bile duct. Clonorchis sinensis infection was detected serologically in 88.3% (38 of 43 cases) among C. sinensis egg positive subjects by the immunoaffinity chromatography using a specific antigen for C. sinensis. For differential diagnosis of the liver and intestinal flukes, more precise PCR and nucleotide sequencing for copro-DNA were performed for 46 egg positive cases. Mixed infections with C. sinensis and Metagonimus yokogawai were detected in 8 of 46 egg positive cases, whereas 29 specimens were positive for Haplorchis taichui. Ultrasonographic findings and immunoaffinity chromatography results showed usefulness, even in a limited way, in figuring out of the liver fluke endemicity.

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UCI(KEPA) : I410-ECN-0101-2014-510-002534936