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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.6
- 수록면
- 350 - 356 (7page)
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This experiment was executed with four week Sprague-Dawley rats in order to examine an effect that swimming exercise had on brain derived neurotrophic factor(BDNF) protein expression in the brain of the adolescent rats. The control and exercise groups were classified into swimming 1 day(n=10), 3 days(n=10), and 7 days(n=10) groups. BDNF protein expression was observed and the results as following were gained in using ELISA(Enzyme -linked immunoAssay) after swimming exercise was practiced an hour a day. In the cerebral cortex the BDNF expression by swimming exercise was increased in 1 day, 3 days, and 7 days and the significant difference was observed statistically(p<0.001). In the cerebellum the BDNF expression of the exercise groups by swimming exercise was increased in 1 day, 3 days, and 7 days as compared with the control groups and the significant difference was observed(p<0.001). In all of cerebral cortex and cerebellum the BDNF expression was increased more in 7days than in 1day so statistical significance was found. It showed the tendency to be increased in 3 days as compared with 1 day, but statistical significance was not found. In the hippocampus the BDNF expression of the exercise groups by swimming exercise was increased in 1 day, 3 days, and 7 days as compared with the control groups so the significant difference was observed statistically. Also It was increased more in 3 and 7 days than in 1 day, and most in 7 days so statistical significance was found(p<0.001). In cerebral cortex, cerebellum and specially hippocampus the BDNF expression was increased conspicuously. These results show that increase of BDNF protein synthesis by swimming exercise is judged to help to being proliferation, differentiation and formation of the adolescent brain cell and is thought to be related to the improvement of learning and memory at second hand.
목차
Abstract
1. 서론
2. 연구 방법
3. 연구 결과
4. 논의
5. 결론
인용문헌
참고문헌 (44)
참고문헌 신청
1. [학술지(정기간행물)] - Adard, P. A. / 2004 / The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise / Neurosci Lett 363 : 43 ~ 48
2. [학술지(정기간행물)] - Bekinschtein, P. / 2008 / BDNF is essential to promote persistence of long-term memory storage / Proc. Natl. Acad. Sci 105 : 2711 ~ 2716
3. [학술지(정기간행물)] - Berchtold, N. C. / 2001 / Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus / Eur J Neurosci 14 : 1992 ~ 2002
4. [학술지(정기간행물)] - Berchtold, N. C. / 2005 / Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus / Neuroscience 133 : 853 ~ 861
5. [학술지(정기간행물)] - Castren, E. / 1998 / Regulartion of brain-derived neurotrophic factor mRNA levels in hippocampus by neuronal activity / Prog Brain Res 117 : 57 ~ 64
2. [학술지(정기간행물)] - Bekinschtein, P. / 2008 / BDNF is essential to promote persistence of long-term memory storage / Proc. Natl. Acad. Sci 105 : 2711 ~ 2716
3. [학술지(정기간행물)] - Berchtold, N. C. / 2001 / Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus / Eur J Neurosci 14 : 1992 ~ 2002
4. [학술지(정기간행물)] - Berchtold, N. C. / 2005 / Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus / Neuroscience 133 : 853 ~ 861
5. [학술지(정기간행물)] - Castren, E. / 1998 / Regulartion of brain-derived neurotrophic factor mRNA levels in hippocampus by neuronal activity / Prog Brain Res 117 : 57 ~ 64
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UCI(KEPA) : I410-ECN-0101-2014-500-003186221