지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.9
- 수록면
- 151 - 156 (6page)
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Objectives：It has been reported that higher percentage of B cells react with monoclonal D8/17 antibody in patients with rheumatic fever, childhood onset obsessive-compulsive disorder, Tourette’ disorder, or prepubertal anorexia nervosa. The purpose of this study is to replicate the previous studies in a Korean young population with tic disorder and to identify any relationship between D8/17 and clinical symptoms.
Methods：The binding of D8/17 to B cells was determined in patients with tic disorder (N=21) and healthy controls (N=9) by Fluorescence-Activated Cell Sorter analysis.
Results：In the sample examined by this study, the average percentage of B cells expressing D8/17 in tic disorder was 2.05%; healthy controls was 3.15%. No statistically significant differences were found in the mean percentages of D8/17 between the two groups.
Conclusion：The expression of D8/17 in B cells was very low in this study. No subjects with tic disorder or healthy controls was above 12% in D8/17 positive proportion. Further studies, including higher number of patients and control group members, should be performed.
Methods：The binding of D8/17 to B cells was determined in patients with tic disorder (N=21) and healthy controls (N=9) by Fluorescence-Activated Cell Sorter analysis.
Results：In the sample examined by this study, the average percentage of B cells expressing D8/17 in tic disorder was 2.05%; healthy controls was 3.15%. No statistically significant differences were found in the mean percentages of D8/17 between the two groups.
Conclusion：The expression of D8/17 in B cells was very low in this study. No subjects with tic disorder or healthy controls was above 12% in D8/17 positive proportion. Further studies, including higher number of patients and control group members, should be performed.
목차
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방법
결과
고찰
결론
References
참고문헌 (24)
참고문헌 신청
1. [기타자료] - American Psychiatric Association / 2000 / Diagnostic and Statistical Manual of Mental Disorder / American Psychiatric Association
2. [학술지(정기간행물)] - Leckman JF / 2002 / Tourette’s syndrome / Lancet 360 : 1577 ~ 1586
3. [학술지(정기간행물)] - Swedo SE / 1998 / Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases / Am J Psychiatry 155 : 264 ~ 271
4. [학술지(정기간행물)] - Cardona F / 2001 / Group A streptococcal infections and tic disorders in an Italian pediatric population / J Pediatr 138 : 71 ~ 75
5. [학술지(정기간행물)] - Martino D / 2009 / Immunopathogenic mechanisms in tourette syndrome: a critical review / Mov Disord 24 : 1267 ~ 1279
2. [학술지(정기간행물)] - Leckman JF / 2002 / Tourette’s syndrome / Lancet 360 : 1577 ~ 1586
3. [학술지(정기간행물)] - Swedo SE / 1998 / Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases / Am J Psychiatry 155 : 264 ~ 271
4. [학술지(정기간행물)] - Cardona F / 2001 / Group A streptococcal infections and tic disorders in an Italian pediatric population / J Pediatr 138 : 71 ~ 75
5. [학술지(정기간행물)] - Martino D / 2009 / Immunopathogenic mechanisms in tourette syndrome: a critical review / Mov Disord 24 : 1267 ~ 1279
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