지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.6
- 수록면
- 13 - 16 (4page)
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The lung is the most frequent extra-abdominal metastatic site for hepatocellular carcinoma (HCC) and colorectal cancer. Pulmonary metastasis was reported in 10% of the patients treated with curative surgery for colorectal cancer. Extrahepatic metastases of HCC have been reported to occur in 14%-42% of the patients with pulmonary metastasis occurring in 50%-60%. Systemic chemotherapy has largely been ineffective in the management of pulmonary metastasis leaving surgery as the proven treatment of choice for treating resectable lung metastasis. Patient selection is the key to achieving successful surgical resection of pulmonary metastases. All pulmonary metastases should be removed when perfoming the metastasectomy and wedge resection has usually been found to be sufficient although pneumonectomy may be necessary in some cases. Factors to consider in determining the surgical approach include the size, number and location of the metastatic lesion. At the time of surgery, obtaining a clear resection margin with as little normal lung tissue as possible is mandatory to reduce the possibility of local recurrence. While the median survival and 1-year survival rate of HCC patients with pulmonary metastasis treated with chemotherapy were 4.6-14.0 months and 20%-30%, respectively, the 5-year survival rate of patients undergoing metastasectomy was reported to be about 25%-35%. The reported 5-year survival rates of patients with colorectal cancer after metastasectomy ranged between 24% and 63%. Although several studies have investigated the prognostic factors for survival in HCC patients undergoing pulmonary metastasectomy, the prognostic factors remain undefined. In case of colorectal cancer, completeness of the pulmonary metastases resection, preoperative carcinoembryonic antigen level, and presence of intrathoracic lymph node metastasis were found to be significant prognostic factors. Resection of pulmonary metastases confers a survival benefit to a select patient and may be recommended as a good treatment option in those patients satisfying the conditions for optimal outcome.
목차
서론
전이성 폐암의 수술적 적응 및 평가
수술 수기의 종류
전이성 폐암의 수술 성적 및 예후인자
결론
REFERENCES
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