지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Journal of the Korean Surgical Society Vol.85 No.5
- 발행연도
- 2013.11
- 수록면
- 212 - 218 (7page)
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초록· 키워드
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Purpose: Prognostic factors for distal bile duct cancer are contentious. This study was conducted to analyze the prognostic factors of distal bile duct cancer after surgery with the aim of identifying those associated with diminished survival.
Methods: Two hundred forty-one patients who underwent pylorus-preserving pancreaticoduodenectomy (PPPD) or Whipple procedure in our tertiary hospital from February 1995 to June 2011 were retrospectively analyzed. All patients were pathologically proven to have distal bile duct adenocarcinoma. Postoperative complications, survival, and well-known prognostic factors after resection for distal bile duct cancer were investigated.
Results: Preoperative elevated carbohydrate antigen 19-9 (CA 19-9) level (P =0.006), positive resection margin (P < 0.001), advanced T stage (P = 0.043), and lymph node metastasis (P = 0.002) were significantly independent worse prognostic indicators by multivariate analysis of resectable distal bile duct cancer.
Conclusion: R0 resection is the most important so that frozen sections should be utilized aggressively during each operation. For the distal bile duct cancer with elevated preoperative CA 19-9 level or advanced stage, further study on postoperative adjuvant treatment may be warranted.
Methods: Two hundred forty-one patients who underwent pylorus-preserving pancreaticoduodenectomy (PPPD) or Whipple procedure in our tertiary hospital from February 1995 to June 2011 were retrospectively analyzed. All patients were pathologically proven to have distal bile duct adenocarcinoma. Postoperative complications, survival, and well-known prognostic factors after resection for distal bile duct cancer were investigated.
Results: Preoperative elevated carbohydrate antigen 19-9 (CA 19-9) level (P =0.006), positive resection margin (P < 0.001), advanced T stage (P = 0.043), and lymph node metastasis (P = 0.002) were significantly independent worse prognostic indicators by multivariate analysis of resectable distal bile duct cancer.
Conclusion: R0 resection is the most important so that frozen sections should be utilized aggressively during each operation. For the distal bile duct cancer with elevated preoperative CA 19-9 level or advanced stage, further study on postoperative adjuvant treatment may be warranted.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (21)
참고문헌 신청
1. [단행본] - The Korea Central Cancer Registry NCC / 2011 / Annual report of cancer statistics in Korea in 2009 / Ministry of Health and Wellfare
2. [학술지(정기간행물)] - Sako K / 1957 / Carcinoma of the extrahepatic bile ducts; review of the literature and report of six cases / Surgery 41 : 416 ~ 437
3. [단행본] - Edge SB / 2010 / AJCC cancer staging manual. 7th ed / Springer
4. [학술지(정기간행물)] - Tompkins RK / 1981 / Prognostic factors in bile duct carcinoma: analysis of 96 cases / Ann Surg 194 : 447 ~ 457
5. [학술지(정기간행물)] - Fernandez-Ruiz M / 2009 / Comorbidity negatively influences prognosis in patients with extrahepatic cholangiocarcinoma / World J Gastroenterol 15 : 5279 ~ 5286
2. [학술지(정기간행물)] - Sako K / 1957 / Carcinoma of the extrahepatic bile ducts; review of the literature and report of six cases / Surgery 41 : 416 ~ 437
3. [단행본] - Edge SB / 2010 / AJCC cancer staging manual. 7th ed / Springer
4. [학술지(정기간행물)] - Tompkins RK / 1981 / Prognostic factors in bile duct carcinoma: analysis of 96 cases / Ann Surg 194 : 447 ~ 457
5. [학술지(정기간행물)] - Fernandez-Ruiz M / 2009 / Comorbidity negatively influences prognosis in patients with extrahepatic cholangiocarcinoma / World J Gastroenterol 15 : 5279 ~ 5286
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