Real-time Assay of Toxic Lead in In Vivo Living Plant Tissue

SuwYoung Ly; Nack Joo Kim; Minsang Youn; Yongwook Kim; Yeolmin Sung; Dohoon Kim; Tackhyun Chung

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자료유형: 학술저널

저자정보: SuwYoung Ly (Seoul National University of Science and Technology) Nack Joo Kim (Seoul National Univ. of Science and Technology) Minsang Youn (Shinil High School) Yongwook Kim (Shinil High School) Yeolmin Sung (Shinil High School) Dohoon Kim (Shinil High School) Tackhyun Chung (Shinil High School)

저널정보: 한국독성학회 Toxicological Research Toxicological Research Vol.29 No.4

발행연도: 2013.12

수록면: 293 - 298 (6page)

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A method of detecting lead was developed using square wave anodic stripping voltammetry (SWASV) with DNA-carbon nanotube paste electrode (CNTPE). The results indicated a sensitive oxidation peak current of lead on the DNA-CNTPE. The curves were obtained within a concentration range of 50 ngL-1-20 mgL-1 with preconcentration time of 100, 200, and 400 sec at the concentration of mgL-1, μgL-1, and ngL-1, respectively. The observed relative standard deviation was 0.101% (n = 12) in the lead concentration of 30.0 μgL.1 under optimum conditions. The low detection limit (S/N) was pegged at 8 ngL-1 (2.6 × 10-8 M). Results showed that the developed method can be used in real-time assay in vivo without requiring any pretreatment and pharmaceutical samples, and food samples, as well as other materials requiring water source contamination analyses.

#DNA-CNTPE #Lead anodic stripping voltammetry #Low concentration #In vivo #Plant #Tap water

참고문헌 (28)

참고문헌 신청

Roscoe, R. J. / 1999 / Blood lead levels among children of lead-exposed workers: A meta-analysis / Am. J. Ind. Med. 36:475~481

Di Nezio, M. S. / 2004 / A sensitive spectrophotometric method for lead determination by flow injection analysis with on-line preconcentration / Talanta 63:405~409

Silbergeld, E. K. / 2000 / Lead as a carcinogen: experimental evidence and mechanisms of action / Am. J. Ind. Med. 38:316~323

Ariza, M. E. / 1999 / Lead and mercury mutagenesis: Type of mutation dependent upon metal concentration / J. Biochem. Mol. Toxicol. 13:107~112

Heo, Y. / 1998 / Differential effects of lead and cAMP on development and activities of Th1- and Th2-lymphocytes / Toxicol. Sci. 43:172~185

이 논문의 저자 정보

이수영

소속기관 Seoul National University of Science and Technology

주요연구분야 의약학 > 기초의학 > 예방의학·직업환경의학 자연과학 > 화학

논문수 13 이용수 273

Nack Joo Kim

소속기관 Seoul National Univ. of Science and Technology