지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Purpose: This study was to identify factors predicting the occurrence of depression among patients with hepatitis C treated with Peg-interferon. Methods: The subjects were 134 patients treated with Peg-interferon after the diagnosis with hepatitis C at the D University Hospital and 3 hospitals located in Busan, South Korea. The predictors of depression were identified by measuring the general characteristics of the subjects and their disease-related characteristics, social support, sleep disorders, and degree of side effects by interferon. The data were analyzed with a t-test, ANOVA, and logistic regression using the SPSS/WIN 18.0 program. Results: Sixty-six point four percent of the subjects suffered from mild to more severe depression. Fatigue, hair loss, itching, and sleep disorders turned out to be significant predictors. In addition, the explanatory power of these variables for the occurrence of depression was 70%. Conclusion: Sleep disorders and drug side effects were determined to have significant influence on the development of depression in hepatitis C patients treated with Peg-interferon. Therefore, the development of nursing intervention programs aimed to prevent depression by effectively managing sleep disorders and side effects is mandated in future to help the given population.
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연구방법
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REFERENCES
참고문헌 (26)
참고문헌 신청
1. [학술지(정기간행물)] - Almeida, A. G. / 2010 / Can antidepressants prevent interferon-alpha-induced depression? / General Hospital Psychiatry 32 : 401 ~ 405
2. [학술지(정기간행물)] - Blasiole, J. A. / 2006 / Mental and physical symptoms associated with lower social support for patients with hepatitis C / World Journal of Gastroenterology 12 : 4665 ~ 4672
3. [학술지(정기간행물)] - Bonaccorso, S. / 2002 / Depression induced by treatment with interferon in patients affected by hepatitis C virus / Jour nal of Affective Disorders 72 : 237 ~ 241
4. [학술지(정기간행물)] - Capuron, L. / 2004 / Baseline mood and psychosocial characteristics of patients developing depressive symptoms during interleukin-2 and/or interferon-alpha cancer therapy / Brain, Behavior, and Immunity 18 : 205 ~ 213
5. [학술지(정기간행물)] - Carroll, V. K. / 2009 / Is a medical illness causing your patient's depression? / Current psychiatry 8 (8) : 43 ~ 54
2. [학술지(정기간행물)] - Blasiole, J. A. / 2006 / Mental and physical symptoms associated with lower social support for patients with hepatitis C / World Journal of Gastroenterology 12 : 4665 ~ 4672
3. [학술지(정기간행물)] - Bonaccorso, S. / 2002 / Depression induced by treatment with interferon in patients affected by hepatitis C virus / Jour nal of Affective Disorders 72 : 237 ~ 241
4. [학술지(정기간행물)] - Capuron, L. / 2004 / Baseline mood and psychosocial characteristics of patients developing depressive symptoms during interleukin-2 and/or interferon-alpha cancer therapy / Brain, Behavior, and Immunity 18 : 205 ~ 213
5. [학술지(정기간행물)] - Carroll, V. K. / 2009 / Is a medical illness causing your patient's depression? / Current psychiatry 8 (8) : 43 ~ 54
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UCI(KEPA) : I410-ECN-0101-2015-510-001433878