The Line-Of-Sight stabilization system is designed to minimize the error of Line-Of-Sight under the disturbing circumstances. In order to control this system more accurately and reduce the level of the disturbance, adding an isolator is mostly considered. However, it is difficult to predict the exact the behavior of the isolator and the effect of a stabilization Error. Therefore, the simulation model of the control system using co-simulation with Adams and matlab simulink is presented and the effects of the isolation properties are reviewed.