지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives: This was a retrospective case series about the clinical effect of integrated approach with behavior therapy for obstructive sleep apnea (OSA).
Methods: Medical records of twelve patients with OSA who were treated with behavior modification including nasal breathing with oral appliances and sleep in lateral position, oral administration of herbal medicines and acupuncture treatment between January and September of 2013 were reviewed. Apnea-hypopnea index (AHI), day time sleepiness, apneas and hypopneas counts during sleep, risk indicator (RI), oxygen desaturation index, average saturation during sleep, lowest desaturation, lowest saturation, snoring events ratio and number of desaturations (%) were assessed before and after treatments with the ApneaLink device, which is a portable diagnostic apparatus for monitoring airflows of the patient"s breath at home.
Results: After an average 62.67 (SD 37.16) days of treatment, AHI (from 17.67, 12.79 to 8.75, 8.25, p=0.007), RI (from 22.00, 13.26 to 12.09, 8.03, p=0.004), oxygen desaturation index (from 17.33, 12.17 to 8.17, 7.86, p=0.005), and number of desaturations (from 7.00 times, 9.79 to 0.92 times, 1.39, p=0.044) showed significant improvement. Daytime sleepiness improved from 6.5 (3.2) to 3.8 (1.8) but there was no significant difference after treatment (p=0.17). No adverse events related to treatment were observed during participation in the treatment.
Conclusion: From this case series, we found that behavior modification with herbal medication and acupuncture may be effective for improving sleep apnea without serious adverse events. Future randomized controlled trials with larger sample size will be necessary for concrete evidence on the benefit of this integrated treatment for OSA.
Methods: Medical records of twelve patients with OSA who were treated with behavior modification including nasal breathing with oral appliances and sleep in lateral position, oral administration of herbal medicines and acupuncture treatment between January and September of 2013 were reviewed. Apnea-hypopnea index (AHI), day time sleepiness, apneas and hypopneas counts during sleep, risk indicator (RI), oxygen desaturation index, average saturation during sleep, lowest desaturation, lowest saturation, snoring events ratio and number of desaturations (%) were assessed before and after treatments with the ApneaLink device, which is a portable diagnostic apparatus for monitoring airflows of the patient"s breath at home.
Results: After an average 62.67 (SD 37.16) days of treatment, AHI (from 17.67, 12.79 to 8.75, 8.25, p=0.007), RI (from 22.00, 13.26 to 12.09, 8.03, p=0.004), oxygen desaturation index (from 17.33, 12.17 to 8.17, 7.86, p=0.005), and number of desaturations (from 7.00 times, 9.79 to 0.92 times, 1.39, p=0.044) showed significant improvement. Daytime sleepiness improved from 6.5 (3.2) to 3.8 (1.8) but there was no significant difference after treatment (p=0.17). No adverse events related to treatment were observed during participation in the treatment.
Conclusion: From this case series, we found that behavior modification with herbal medication and acupuncture may be effective for improving sleep apnea without serious adverse events. Future randomized controlled trials with larger sample size will be necessary for concrete evidence on the benefit of this integrated treatment for OSA.
목차
Introduction
Methods
Interventions
Outcome assessment
Statistical analysis
Results
Discussion
Reference
참고문헌 (22)
참고문헌 신청
Oksenberg A / 2000 / Association of body position with severity of apneic events in patients with severe nonpositional obstructive sleep apnea / Chest 118:1018~1024
Epstein LJ / 2009 / Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults / Journal of Clinical Sleep Medicine :JCSM : official publication of the American Academy of Sleep Medicine 5:263~276
Oksenberg A / 2013 / Are we missing a simple treatment for most adults sleep apnea patients? The avoidance of the supine sleep position / Journal of Sleep Research
Koutsourelakis I / 2006 / Obstructive sleep apnoea and oral breathing in patients free of nasal obstruction / The European Respiratory Journal 28:1222~1228
Lee SH / 2007 / How does open-mouth breathing influence upper airway anatomy? / LARYNGOSCOPE 117:1102~1106
Epstein LJ / 2009 / Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults / Journal of Clinical Sleep Medicine :JCSM : official publication of the American Academy of Sleep Medicine 5:263~276
Oksenberg A / 2013 / Are we missing a simple treatment for most adults sleep apnea patients? The avoidance of the supine sleep position / Journal of Sleep Research
Koutsourelakis I / 2006 / Obstructive sleep apnoea and oral breathing in patients free of nasal obstruction / The European Respiratory Journal 28:1222~1228
Lee SH / 2007 / How does open-mouth breathing influence upper airway anatomy? / LARYNGOSCOPE 117:1102~1106
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UCI(KEPA) : I410-ECN-0101-2015-510-002490808