지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.9
- 수록면
- 159 - 168 (10page)
이용수
초록· 키워드
오류제보하기
Pesticides have provided significant benefits including plant disease control and increased crop yields since people developed and utilized them. However, pesticide use is associated with many adverse effects, which necessitate precise toxicological tests and risk assessment. Most of these methods are based on animal studies, but considerations of animal welfare and ethics require the development of alternative methods for the evaluation of pesticide toxicity. Although the usage of laboratory animals is inevitable in scientific evaluation and alternative approaches have limitations in the whole coverage, continuous effort is necessary to minimize animal use and to develop reliable alternative tests for pesticide evaluation. This review discusses alternative approaches for pesticide toxicity tests and hazard evaluation that have been used in peer-reviewed reports and could be applied in future studies based on the critical animal research principles of reduction, replacement, and refinement.
목차
INTRODUCTION
CURRENT ISSUES IN TOXICOLOGICAL TESTS FOR PESTICIDES
IN VITRO ALTERNATIVE PESTICIDE TOXICITY TESTING METHODS
IN VIVO ALTERNATIVE PESTICIDE TOXICITY TESTING METHODS
IN SILICO ALTERNATIVE PESTICIDE TOXICITY TESTING METHODS
POSSIBLE METHODS WIDELY APPLICABLE TO ALTERNATIVE TESTING OF PESTICIDES
CONCLUSIONS AND EXPECTED FUTURE OF PESTICIDE TOXICOLOGY
REFERENCES
참고문헌 (56)
참고문헌 신청
Korea Ministry of Government Legislation / Agricultural chemicals regulation law
Korea Crop Protection Association / 2005 / Safety of Pesticides-A Great Difference between Original Toxicity and Product Toxicity / Life and Pesticides :38~39
Russell, W.M.S. / 1959 / The principles of humane experimental technique / Methuen
Gupta, K. / 2005 / Ensuring quality of in vitro alternative test methods:Issues and answers / Regul. Toxicol. Pharmacol 43:219~224
Korea Ministry of Government Legislation / Animal Protection Law
Korea Crop Protection Association / 2005 / Safety of Pesticides-A Great Difference between Original Toxicity and Product Toxicity / Life and Pesticides :38~39
Russell, W.M.S. / 1959 / The principles of humane experimental technique / Methuen
Gupta, K. / 2005 / Ensuring quality of in vitro alternative test methods:Issues and answers / Regul. Toxicol. Pharmacol 43:219~224
Korea Ministry of Government Legislation / Animal Protection Law
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UCI(KEPA) : I410-ECN-0101-2015-510-002798750