This study investigated the differences between emotional parameters BDI, VHI, STAI-X-Ⅰand STAI-X-II according to the menstrual cycles of the female and the relation between changes of the depression index and voice characteristics (jitter, shimmer, CPP, HNR, pF0·F1·F2·F3, sF0, sF4, sB1, H1<SUB>c/u</SUB>, A1u, A3<SUB>c</SUB>, H1A3<SUB>c/u</SUB>, H1A1<SUB>u</SUB>). Twenty three females (30 ± 4.4 years old) living in Seoul and Gyeonggi Province were participated in this study to answer the questionnaires and record their voice. The participants prolonged /a/ vowel for 5 seconds in a natural condition for their voice recording. Voice data were analyzed using the Matlab and Praat program. A t-test and a correlation analysis were conducted by using SPSS for the statistical analysis. The results are as follows. First, the BDI is significantly higher in group Ⅰ(lurear phase contrast the menstrual period) and group Ⅱ (follicular phase against the menstrual period) than group Ⅲ (luteal phase for follicular phase) (p<.05). Second, shimmer, CPP, pF0 showed a statistically high correlation regarding the BDI in group Ⅰ(lurear phase contrast the menstrual period). Voice parameters may be useful as supplement in evaluating the emotional change in the phase of menstrual cycle.