지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.9
- 수록면
- 156 - 162 (7page)
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초록· 키워드
오류제보하기
Objectives：The aim of this study was to estimate the prevalences of electroencephalographic (EEG) abnormalities and epilepsy in children and adolescents with autism spectrum disorder (ASD). In addition, we intended to identify demographic and clinical correlates of epilepsy in ASD.
Methods：A total of 140 children and adolescents (age 7.3±4.8 yrs, 106 boys) with ASD underwent EEG from January 2010 to December 2013 at Asan Medical Center. Medical records were reviewed for demographic information, clinical characteristics, psychiatric diagnoses and comorbidities, EEG findings and neurological diagnoses.
Results：The prevalences of EEG abnormalities and epilepsy in children and adolescents with ASD was 62.1% and 38.6%, respectively. In subjects with seizure-like movements, EEG abnormalities and epilepsy were more frequent than those without seizure-like movements (EEG abnormalities : 92.5% vs. 43.7%, p<.001 ; epilepsy : 90.6% vs. 5.7%, p<.001). ASD subjects who had epilepsy were older (p=.001), had lower full scale intelligence quotient (p<.001) and took more antipsychotics (p=.006) than those who did not.
Conclusion：The prevalences of EEG abnormalities and epilepsy in our sample were similar to those from Western countries. Our results suggested a possible association of older age, lower intelligence quotient, and antipsychotics use with epilepsy in ASD. Conduct of further prospective study in a larger sample is needed.
Methods：A total of 140 children and adolescents (age 7.3±4.8 yrs, 106 boys) with ASD underwent EEG from January 2010 to December 2013 at Asan Medical Center. Medical records were reviewed for demographic information, clinical characteristics, psychiatric diagnoses and comorbidities, EEG findings and neurological diagnoses.
Results：The prevalences of EEG abnormalities and epilepsy in children and adolescents with ASD was 62.1% and 38.6%, respectively. In subjects with seizure-like movements, EEG abnormalities and epilepsy were more frequent than those without seizure-like movements (EEG abnormalities : 92.5% vs. 43.7%, p<.001 ; epilepsy : 90.6% vs. 5.7%, p<.001). ASD subjects who had epilepsy were older (p=.001), had lower full scale intelligence quotient (p<.001) and took more antipsychotics (p=.006) than those who did not.
Conclusion：The prevalences of EEG abnormalities and epilepsy in our sample were similar to those from Western countries. Our results suggested a possible association of older age, lower intelligence quotient, and antipsychotics use with epilepsy in ASD. Conduct of further prospective study in a larger sample is needed.
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결론
References
참고문헌 (47)
참고문헌 신청
1. [단행본] - American Psychiatric Association / 2013 / Diagnostic and Statistical Manual of Mental Disorders: DSM-5 / American Psychiatric Association
2. [단행본] - American Psychiatric Association / 2000 / Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR / American Psychiatric Association
3. [학술지(정기간행물)] - Volkmar FR / 2004 / Schultz RT, Klin A. Autism and pervasive developmental disorders / J Child Psychol Psychiatry 45 : 135 ~ 170
4. [학술지(정기간행물)] - 장원석 / 2006 / 자폐 스펙트럼 장애 아동의 언어 능력에 미치는 도네페질의 효과 / 신경정신의학 45 (1) : 64 ~ 68
5. [학술지(정기간행물)] - Baird G / 2006 / Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP) / Lancet 368 : 210 ~ 215
2. [단행본] - American Psychiatric Association / 2000 / Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR / American Psychiatric Association
3. [학술지(정기간행물)] - Volkmar FR / 2004 / Schultz RT, Klin A. Autism and pervasive developmental disorders / J Child Psychol Psychiatry 45 : 135 ~ 170
4. [학술지(정기간행물)] - 장원석 / 2006 / 자폐 스펙트럼 장애 아동의 언어 능력에 미치는 도네페질의 효과 / 신경정신의학 45 (1) : 64 ~ 68
5. [학술지(정기간행물)] - Baird G / 2006 / Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP) / Lancet 368 : 210 ~ 215
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UCI(KEPA) : I410-ECN-0101-2015-510-002728416