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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.9
- 수록면
- 112 - 122 (11page)
이용수
초록· 키워드
오류제보하기
UG0712 is a new ginsenoside extract processed from ginseng leaves. A subchronic toxicity study of UG0712 was conducted in male and female SD rats. Rats were treated with UG0712 at doses of 100, 400 and 1,600 mg/kg/day for 13 weeks, and observed followed by 4-week recovery period at a highest dose. No-treatment-related effects were observed regarding the mortality, ophthalmic examination, urinalysis and histopathology. Although the changes in clinical sign, body weight, organ weight, hematology, and serum biochemistry were observed, they were temporal and pharmacological effects. Based on the present experiment conditions, the no observed adverse effect level was considered to be more than 1,600 mg/kg/day in both sexes of rats.
목차
Materials and Methods
Results
Discussion
References
참고문헌 (21)
참고문헌 신청
1. [학술지(정기간행물)] - Yun TK. / 2001 / Brief introduction of Panax ginseng C.A. Meyer / J Korean Med Sci 16 (Supp l) : S3 ~ S5
2. [학술지(정기간행물)] - Kiefer D. / 2003 / Panax ginseng / Am Fam Physician 68 (8) : 1539 ~ 1542
3. [학술지(정기간행물)] - Leung KW. / 2010 / Pharmacology of ginsenosides : a literature review / Chin Med 5 : 20 ~
4. [학술지(정기간행물)] - 김현숙 / 2004 / Effects of Ginsenosides Rg3 and Rh2 on the Proliferation of Prostate Cancer Cells / Archives of Pharmacal Research 27 (4) : 429 ~ 435
5. [학술지(정기간행물)] - 김대현 / 2013 / Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-kB in LPS-stimulated RAW264.7 cells and mouse liver / Journal of Ginseng Research 37 (1) : 54 ~ 63
2. [학술지(정기간행물)] - Kiefer D. / 2003 / Panax ginseng / Am Fam Physician 68 (8) : 1539 ~ 1542
3. [학술지(정기간행물)] - Leung KW. / 2010 / Pharmacology of ginsenosides : a literature review / Chin Med 5 : 20 ~
4. [학술지(정기간행물)] - 김현숙 / 2004 / Effects of Ginsenosides Rg3 and Rh2 on the Proliferation of Prostate Cancer Cells / Archives of Pharmacal Research 27 (4) : 429 ~ 435
5. [학술지(정기간행물)] - 김대현 / 2013 / Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-kB in LPS-stimulated RAW264.7 cells and mouse liver / Journal of Ginseng Research 37 (1) : 54 ~ 63
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UCI(KEPA) : I410-ECN-0101-2015-500-002710867