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논문 기본 정보

자료유형
학술저널
저자정보
Min-Jeong Kim (Kyungpook National University) Hyun-Jin Kim (Kyungpook National University)
저널정보
대한치과재료학회 대한치과재료학회지 대한치과재료학회지 제41권 제4호
발행연도
2014.12
수록면
319 - 324 (6page)
DOI
10.14815/kjdm.2014.41.4.319

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초록· 키워드

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In this study, to evaluation the chlorhexidine (CHX) release from the modified 4-META/MMA-TBB (4-META) resin filled with pre-polymerized filler containing human serum albumin (HSA) nanoparticles. The 4-META resin and modified 4-META resin specimens containing the CHX-loaded HSA nanoparticles were prepared as follows manufacturer. The morphology of the resin containing nanoparticles were observed using scanning electron microscopy (SEM) and in vitro release profile of CHX from the resin was measured by placing the samples in phosphate-buffered saline (PBS, pH 7.4) at 37˚C for up to 30 days. The SEM image of the resin clearly shows that the CHX-loaded HSA nanoparticles were homogeneously dispersed and well-incorporated in the two different resin matrix. Moreover, CHX was successfully released from the two different resin matrix for a long period of time (up to 30 days incubation time). However, in comparison with the 4-META resin containing CHX-loaded HSA nanoparticles, the release profile of the modified 4-META resin containing CHX-loaded HSA nanoparticles showed a lower amount of CHX released over the study period. The flexural strength and tensile bond strength remains unchanged by incorporation of CHX-loaded HSA nanoparticles and CHX powder in two different 4-META resin (p > 0.05).

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UCI(KEPA) : I410-ECN-0101-2016-515-000931090