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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
대한지역사회영양학회 대한지역사회영양학회지 대한지역사회영양학회지 제10권 제5호
발행연도
2005.10
수록면
615 - 622 (8page)

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Folate and Vitamin B₁₂ are essential nutrients important during pregnancy. This study was conducted to evaluate the folate and vitamin B₁₂ nutritional status of Korean pregnant women and to investigate the relationship between maternal-umbilical cord serum folate and vitamin B12 levels pregnancy outcomes. Dietary intakes of the pregnant women were estimated by 24 hour-recall (3 times). Serum folate and vitamin B12 levels in maternal blood and umbilical cord of 27 pregnant women at 1'st-, 2'nd-, 3'rd- trimester and delivery were measured by RIA (radioimmuno assay), respectively. Means of folate and vitamin B₁₂ intake were 283.53 ± 58.01 ㎍/day and 2.99 ± 1.32 ㎎/day, respectively. Maternal mean serum folate levels of the trimester and delivery were 9.75 ± 3.60 ng/㎖, 10.46 ± 4.63 ng/㎖, 10.71 ± 4.14 ng/㎖ and 15.05 ± 7.04 ng/㎖. Those maternal levels were significantly lower than that of umbilical cord blood (23.99 ± 9.42 ng/㎖). Serum vitamin B₁₂ level of maternal trimester and delivery were 479.07 ± 137.56 pg/㎖, 310.96 ± 137.56 pg/㎖, 308.22 ± 74.65 pg/㎖, and 295.67 ± 93.56 pg/㎖, which were significantly lower than those of umbilical cord blood (500.13 ± 185.60 ng/㎖). This finding indicated that the uptake of folate and vitamin B₁₂ in the fetus may be due to an active placental transport mechanism. Maternal serum level correlated positively with those of umbilical cord blood, showing that folate and vitamin B₁₂ concentration of umbilical cord blood might be affected by maternal status. There was no significant correlation between the serum folate levels in maternal-umbilical cord blood and the pregnancy outcomes. However, maternal vitamin B₁₂ level at 1'st trimester was significant positive correlation between the gestational age except for birth weight and weight gain.

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