The present study examined the mediating effects of emotion regulation in the relationships between resilience and sport coping for professional soccer players. The smaple of this study was selected from professional soccer player using a stratified cluster sampling technqiue. A total of 158 participants’ response were used to conduct data analysis. SPSS 20.0 was used for descriptive statistics, AMOS 20.0 was utilized for confirmatory factor analysis and structural equation model. The resutsl of the analysis are as follows: First, the professional soccer players’ resilience influence the emotion regulation. Secondly, the professional soccer players’ emotion regulation influence the sport coping. Finally, the professional soccer players’ resilience influence the sport coping. Also the emotion regulation to mediate the relationship between resilience and sport coping.