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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.12
- 수록면
- 287 - 293 (7page)
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초록· 키워드
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Noroviruses (NoV) are the major viral pathogen that causes epidemic acute gastroenteritis and outbreaks of food-borne illness. The major genotypes responsible for the epidemics of NoV are GII.4 and GII.3. However, most studies of NoV have been associated with GII.4 genotype and only few studies have been done with GII.3 genotype. Here, we selected 18 GII.3 strains, which recently circulated in Korea, and determined the partial sequences of the capsid gene. Phylogenetic analysis comparing these sequences with 29 reference strains from the GenBank database was performed using the MEGA program. All NoV GII.3 strains formed 2 distinct genetic lineages and variant groups. Lineage A showed 94.1~97.6%, 90.2~94.6% nucleotide identities from lineage B and variant group, respectively. Lineage B showed 90.2~94.6% nucleotide identities from variant group. These different genetic lineages based on the phylogenetic analysis of capsid sequences imply that the circulating Korean NoV GII.3 strains have potential antigenic variation.
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재료 및 방법
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고찰
참고문헌
참고문헌 (23)
참고문헌 신청
1. [학술지(정기간행물)] - Glass RI / 2001 / Gastroenteritis viruses: an overview / Novartis Found Symp 238 : 5 ~ 19
2. [학술지(정기간행물)] - Chikhi-Brachet R / 2002 / Virus Diversity in a Winter Epidemic of Acute Diarrhea in France / J Clin Microbiol 40 : 4266 ~ 4272
3. [학술지(정기간행물)] - Dey SK / 2007 / Molecular and epidemiological trend of norovirus associated gastroenteritis in Dhaka City, Bangladesh / J Clin Virol 40 : 218 ~ 223
4. [학술지(정기간행물)] - Kapikian AZ / 1972 / Visualization by immune electron microscopy of a 27-nm particle associated with acute infectious nonbacterial gastroenteritis / J Virol 10 : 1075 ~ 1081
5. [학술지(정기간행물)] - Kaplan JE / 1982 / Epidemiology of Norwalk gastroenteritis and the role of Norwalk virus in outbreaks of acute nonbacterial gastroenteritis / Ann Intern Med 96 : 756 ~ 761
2. [학술지(정기간행물)] - Chikhi-Brachet R / 2002 / Virus Diversity in a Winter Epidemic of Acute Diarrhea in France / J Clin Microbiol 40 : 4266 ~ 4272
3. [학술지(정기간행물)] - Dey SK / 2007 / Molecular and epidemiological trend of norovirus associated gastroenteritis in Dhaka City, Bangladesh / J Clin Virol 40 : 218 ~ 223
4. [학술지(정기간행물)] - Kapikian AZ / 1972 / Visualization by immune electron microscopy of a 27-nm particle associated with acute infectious nonbacterial gastroenteritis / J Virol 10 : 1075 ~ 1081
5. [학술지(정기간행물)] - Kaplan JE / 1982 / Epidemiology of Norwalk gastroenteritis and the role of Norwalk virus in outbreaks of acute nonbacterial gastroenteritis / Ann Intern Med 96 : 756 ~ 761
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