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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.4
- 수록면
- 41 - 47 (7page)
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초록· 키워드
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Contemporary studies illustrate that peripheral injuries activate glial components of the peripheral and central cellular circuitry. The subsequent release of glial stressors or activating signals contributes to neuropathic pain and neuroinflammation. Recent studies document the importance of glia in the development and persistence of neuropathic pain and neuroinflammation as a connecting link, thereby focusing attention on the glial pathology as the general underlying factor in essentially all age-related neurodegenerative diseases. There is wide agreement that excessive glial activation is a key process in nervous system disorders involving the release of strong pro-inflammatory cytokines, which can trigger worsening of multiple disease states. This review will briefly discuss the recent findings that have shed light on the molecular and cellular mechanisms of glia as a connecting link between neuropathic pain and neuroinflammation.
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참고문헌 (61)
참고문헌 신청
1. [학술지(정기간행물)] - Kriegstein A / 2009 / The glial nature of embryonic and adult neural stem cells / Annu Rev Neurosci 32 : 149 ~ 184
2. [학술지(정기간행물)] - Moalem G / 2006 / Immune and inflammatory mechanisms in neuropathic pain / Brain Res Rev 51 : 240 ~ 264
3. [학술지(정기간행물)] - Aamodt S / 2007 / Focus on glia and disease / Nat Neurosci 10 : 1349 ~
4. [학술지(정기간행물)] - Watkins LR / 2001 / Glial activation: a driving force for pathological pain / Trends Neurosci 24 : 450 ~ 455
5. [학술지(정기간행물)] - McMahon SB / 2005 / Immune and glial cell factors as pain mediators and modulators / Exp Neurol 192 : 444 ~ 462
2. [학술지(정기간행물)] - Moalem G / 2006 / Immune and inflammatory mechanisms in neuropathic pain / Brain Res Rev 51 : 240 ~ 264
3. [학술지(정기간행물)] - Aamodt S / 2007 / Focus on glia and disease / Nat Neurosci 10 : 1349 ~
4. [학술지(정기간행물)] - Watkins LR / 2001 / Glial activation: a driving force for pathological pain / Trends Neurosci 24 : 450 ~ 455
5. [학술지(정기간행물)] - McMahon SB / 2005 / Immune and glial cell factors as pain mediators and modulators / Exp Neurol 192 : 444 ~ 462
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