지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Trichloroethylene (TCE) has been widely used as a degreasing agent in many manufacturing industries. Recently, the International Agency for Research on Cancer presented “sufficient evidence” for the causal relationship between TCE and kidney cancer. The aim of this study was to review the epidemiologic evidences regarding the relationship between TCE exposure and kidney cancer in Korean work environments. The results from the cohort studies were inconsistent, but according to the meta-analysis and case?control studies, an increased risk for kidney cancer was present in the exposure group and the dose?response relationship could be identified using various measures of exposure. In Korea, TCE is a commonly used chemical for cleaning or degreasing processes by various manufacturers; average exposure levels of TCE vary widely. When occupational physicians evaluate work-relatedness kidney cancers, they must consider past exposure levels, which could be very high (>100 ppm in some cases) and associated with jobs, such as plating, cleaning, or degreasing. The exposure levels at a manual job could be higher than an automated job. The peak level of TCE could also be considered an important exposure-related variable due to the possibility of carcinogenesis associated with high TCE doses. This review could be a comprehensive reference for assessing work-related TCE exposure and kidney cancer in Korea.
목차
Abstract
Introduction
Review
Conclusion
References
참고문헌 (28)
참고문헌 신청
NIOSH / 1978 / Special Occupational Hazard Review with Control Recommendations Trichloroethylene :1~59
Dekant W / 1984 / Novel metabolites of trichloroethylene through dechlorination reactions in rats, mice and humans / Biochem Pharmaco 33(13):2021~2027
Guha N / 2012 / Carcinogenicity of trichloroethylene, tetrachloroethylene, some other chlorinated solvents, and their metabolites / Lancet Oncol 13(12):1192~1193
Korea Occupational Safety and Health Agency / A kidney cancer case developed in automobile manufacturing industry
The Korea Central Cancer Registry, National Cancer Center / Annual Report of Cancer Statistics in Korea in 2011
Dekant W / 1984 / Novel metabolites of trichloroethylene through dechlorination reactions in rats, mice and humans / Biochem Pharmaco 33(13):2021~2027
Guha N / 2012 / Carcinogenicity of trichloroethylene, tetrachloroethylene, some other chlorinated solvents, and their metabolites / Lancet Oncol 13(12):1192~1193
Korea Occupational Safety and Health Agency / A kidney cancer case developed in automobile manufacturing industry
The Korea Central Cancer Registry, National Cancer Center / Annual Report of Cancer Statistics in Korea in 2011
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UCI(KEPA) : I410-ECN-0101-2016-517-001953134